A closed-loop brain computer interface for real-time seizure detection and control

Research output: Chapter in Book/Report/Conference proceedingConference contribution

22 Citations (Scopus)

Abstract

The worldwide prevalence of epilepsy is approximately 1%, and 25% of epilepsy patients cannot be treated sufficiently by available therapies. Brain stimulation with closed-loop seizure control has recently been proposed as an innovative and effective alternative. In this paper, a portable closed-loop brain computer interface for seizure control was developed and shown with several aspects of advantages, including high seizure detection rate (92-499% during wake-sleep states), low false detection rate (1.2-2.5%), and small size. The seizure detection and electrical stimulation latency was not greater than 0.6 s after seizure onset. A wireless communication feature also provided flexibility for subjects freeing from the hassle of wires. Experimental data from freely moving rats supported the functional possibility of a real-time closed-loop seizure controller.

Original languageEnglish
Title of host publication2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Pages4950-4953
Number of pages4
DOIs
Publication statusPublished - 2010 Dec 1
Event2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, Argentina
Duration: 2010 Aug 312010 Sep 4

Publication series

Name2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10

Other

Other2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
CountryArgentina
CityBuenos Aires
Period10-08-3110-09-04

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Health Informatics

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  • Cite this

    Liang, S. F., Shaw, F. Z., Young, C. P., Chang, D. W., & Liao, Y. C. (2010). A closed-loop brain computer interface for real-time seizure detection and control. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp. 4950-4953). [5627243] (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10). https://doi.org/10.1109/IEMBS.2010.5627243