A CMOS-compatible biological transducer for creatinine detection: MIP-gate ISFET

Chen Fu Lin, Hann Huei Tsai, Ying Zong Juang, Yan Kuin Su, Wang-Long Li, Ruey Lue Wang, Hung Yin Lin, Jia Yu Guo, Tian Jun Tsai, Bin-Da Liu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In this paper, it demonstrates a CMOS-compatible transducer for creatinine detection. Different with traditional application of ISFET (Ion Selective Field Effect Transistor), it is not for the hydrogen ion detection. To combine the CMOS MEMS platform with MIP (Molecular Imprinting Polymer) micro coating technologies, the developed MIP-gate ISFET could be used for the detecting of creatinine. The experiment results showed that the difference of response current was about 13 A when the concentration was varied from 0.199mg/mL to 0.787mg/mL. Beside, this paper successfully demonstrates the possibility of the liquid isolation and localized MIP coating technology.

Original languageEnglish
Title of host publication2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09
DOIs
Publication statusPublished - 2009 Sep 17
Event2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09 - Chengdu, China
Duration: 2009 Apr 282009 Apr 29

Publication series

Name2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09

Other

Other2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09
CountryChina
CityChengdu
Period09-04-2809-04-29

Fingerprint

Field-effect Transistor
Field effect transistors
Transducer
Transducers
Polymers
Coating
Ions
Coatings
Micro-electro-mechanical Systems
Demonstrate
Hydrogen
Isolation
MEMS
Liquid
Liquids
Experiment
Experiments

All Science Journal Classification (ASJC) codes

  • Hardware and Architecture
  • Electrical and Electronic Engineering
  • Modelling and Simulation

Cite this

Lin, C. F., Tsai, H. H., Juang, Y. Z., Su, Y. K., Li, W-L., Wang, R. L., ... Liu, B-D. (2009). A CMOS-compatible biological transducer for creatinine detection: MIP-gate ISFET. In 2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09 [4960739] (2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09). https://doi.org/10.1109/CAS-ICTD.2009.4960739
Lin, Chen Fu ; Tsai, Hann Huei ; Juang, Ying Zong ; Su, Yan Kuin ; Li, Wang-Long ; Wang, Ruey Lue ; Lin, Hung Yin ; Guo, Jia Yu ; Tsai, Tian Jun ; Liu, Bin-Da. / A CMOS-compatible biological transducer for creatinine detection : MIP-gate ISFET. 2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09. 2009. (2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09).
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abstract = "In this paper, it demonstrates a CMOS-compatible transducer for creatinine detection. Different with traditional application of ISFET (Ion Selective Field Effect Transistor), it is not for the hydrogen ion detection. To combine the CMOS MEMS platform with MIP (Molecular Imprinting Polymer) micro coating technologies, the developed MIP-gate ISFET could be used for the detecting of creatinine. The experiment results showed that the difference of response current was about 13 A when the concentration was varied from 0.199mg/mL to 0.787mg/mL. Beside, this paper successfully demonstrates the possibility of the liquid isolation and localized MIP coating technology.",
author = "Lin, {Chen Fu} and Tsai, {Hann Huei} and Juang, {Ying Zong} and Su, {Yan Kuin} and Wang-Long Li and Wang, {Ruey Lue} and Lin, {Hung Yin} and Guo, {Jia Yu} and Tsai, {Tian Jun} and Bin-Da Liu",
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Lin, CF, Tsai, HH, Juang, YZ, Su, YK, Li, W-L, Wang, RL, Lin, HY, Guo, JY, Tsai, TJ & Liu, B-D 2009, A CMOS-compatible biological transducer for creatinine detection: MIP-gate ISFET. in 2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09., 4960739, 2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09, 2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09, Chengdu, China, 09-04-28. https://doi.org/10.1109/CAS-ICTD.2009.4960739

A CMOS-compatible biological transducer for creatinine detection : MIP-gate ISFET. / Lin, Chen Fu; Tsai, Hann Huei; Juang, Ying Zong; Su, Yan Kuin; Li, Wang-Long; Wang, Ruey Lue; Lin, Hung Yin; Guo, Jia Yu; Tsai, Tian Jun; Liu, Bin-Da.

2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09. 2009. 4960739 (2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - A CMOS-compatible biological transducer for creatinine detection

T2 - MIP-gate ISFET

AU - Lin, Chen Fu

AU - Tsai, Hann Huei

AU - Juang, Ying Zong

AU - Su, Yan Kuin

AU - Li, Wang-Long

AU - Wang, Ruey Lue

AU - Lin, Hung Yin

AU - Guo, Jia Yu

AU - Tsai, Tian Jun

AU - Liu, Bin-Da

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Y1 - 2009/9/17

N2 - In this paper, it demonstrates a CMOS-compatible transducer for creatinine detection. Different with traditional application of ISFET (Ion Selective Field Effect Transistor), it is not for the hydrogen ion detection. To combine the CMOS MEMS platform with MIP (Molecular Imprinting Polymer) micro coating technologies, the developed MIP-gate ISFET could be used for the detecting of creatinine. The experiment results showed that the difference of response current was about 13 A when the concentration was varied from 0.199mg/mL to 0.787mg/mL. Beside, this paper successfully demonstrates the possibility of the liquid isolation and localized MIP coating technology.

AB - In this paper, it demonstrates a CMOS-compatible transducer for creatinine detection. Different with traditional application of ISFET (Ion Selective Field Effect Transistor), it is not for the hydrogen ion detection. To combine the CMOS MEMS platform with MIP (Molecular Imprinting Polymer) micro coating technologies, the developed MIP-gate ISFET could be used for the detecting of creatinine. The experiment results showed that the difference of response current was about 13 A when the concentration was varied from 0.199mg/mL to 0.787mg/mL. Beside, this paper successfully demonstrates the possibility of the liquid isolation and localized MIP coating technology.

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Lin CF, Tsai HH, Juang YZ, Su YK, Li W-L, Wang RL et al. A CMOS-compatible biological transducer for creatinine detection: MIP-gate ISFET. In 2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09. 2009. 4960739. (2009 IEEE Circuits and Systems International Conference on Testing and Diagnosis, ICTD'09). https://doi.org/10.1109/CAS-ICTD.2009.4960739