A comparative study of the physical and mechanical properties of three natural corals based on the criteria for bone-tissue engineering scaffolds

Yu Chun Wu, Tzer-Min Lee, Kuo Hsun Chiu, Shyh-Yu Shaw, Chyun-Yu Yang

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Coral has been used for bone grafts since 1970. Because coral has the advantages of good osteoconduction, biocompatibility, and biodegradation, it is also suitable for scaffolds used in bone-tissue engineering. However, the skeletons of different species of corals often vary significantly, and very few studies focus on the assessment of the permeability and mechanical properties of coral structure. In order to better understand the use of coral in bone tissue-engineering, we selected three typical models (Acropora sp., Goniopora sp., and Porites sp.) to analyze for pore size, porosity, permeability, and mechanical strength. We found Goniopora and Porites had homogenous structure and Acropora had oriented pores and irregular pore size. Acropora had the largest permeability, however, the transverse section was closed and the useful size was limited because of its habitat type. Porites had the smallest pore size and had the lowest permeability. Our data indicated that Goniopora sp. can be considered as the most promising source of scaffolds for bone-tissue engineering because of its high porosity (73%) and that its permeability and mechanics were similar to those in human cancellous bone. In conclusion, we analyzed the impact of the macroporous structure of coral on the permeability and mechanical properties that provide indicators for designing the optimal scaffold for bone-tissue engineering.

Original languageEnglish
Pages (from-to)1273-1280
Number of pages8
JournalJournal of Materials Science: Materials in Medicine
Volume20
Issue number6
DOIs
Publication statusPublished - 2009 Jun 1

Fingerprint

Tissue Scaffolds
Anthozoa
Tissue Engineering
Scaffolds (biology)
Tissue engineering
Permeability
Bone
Physical properties
Bone and Bones
Mechanical properties
Pore size
Porosity
Bone Regeneration
Biodegradation
Mechanics
Biocompatibility
Skeleton
Grafts
Strength of materials
Ecosystem

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

Cite this

@article{eb87a9364ad04968bd22a80d7484eec6,
title = "A comparative study of the physical and mechanical properties of three natural corals based on the criteria for bone-tissue engineering scaffolds",
abstract = "Coral has been used for bone grafts since 1970. Because coral has the advantages of good osteoconduction, biocompatibility, and biodegradation, it is also suitable for scaffolds used in bone-tissue engineering. However, the skeletons of different species of corals often vary significantly, and very few studies focus on the assessment of the permeability and mechanical properties of coral structure. In order to better understand the use of coral in bone tissue-engineering, we selected three typical models (Acropora sp., Goniopora sp., and Porites sp.) to analyze for pore size, porosity, permeability, and mechanical strength. We found Goniopora and Porites had homogenous structure and Acropora had oriented pores and irregular pore size. Acropora had the largest permeability, however, the transverse section was closed and the useful size was limited because of its habitat type. Porites had the smallest pore size and had the lowest permeability. Our data indicated that Goniopora sp. can be considered as the most promising source of scaffolds for bone-tissue engineering because of its high porosity (73{\%}) and that its permeability and mechanics were similar to those in human cancellous bone. In conclusion, we analyzed the impact of the macroporous structure of coral on the permeability and mechanical properties that provide indicators for designing the optimal scaffold for bone-tissue engineering.",
author = "Wu, {Yu Chun} and Tzer-Min Lee and Chiu, {Kuo Hsun} and Shyh-Yu Shaw and Chyun-Yu Yang",
year = "2009",
month = "6",
day = "1",
doi = "10.1007/s10856-009-3695-3",
language = "English",
volume = "20",
pages = "1273--1280",
journal = "Journal of Materials Science: Materials in Electronics",
issn = "0957-4522",
publisher = "Springer New York",
number = "6",

}

TY - JOUR

T1 - A comparative study of the physical and mechanical properties of three natural corals based on the criteria for bone-tissue engineering scaffolds

AU - Wu, Yu Chun

AU - Lee, Tzer-Min

AU - Chiu, Kuo Hsun

AU - Shaw, Shyh-Yu

AU - Yang, Chyun-Yu

PY - 2009/6/1

Y1 - 2009/6/1

N2 - Coral has been used for bone grafts since 1970. Because coral has the advantages of good osteoconduction, biocompatibility, and biodegradation, it is also suitable for scaffolds used in bone-tissue engineering. However, the skeletons of different species of corals often vary significantly, and very few studies focus on the assessment of the permeability and mechanical properties of coral structure. In order to better understand the use of coral in bone tissue-engineering, we selected three typical models (Acropora sp., Goniopora sp., and Porites sp.) to analyze for pore size, porosity, permeability, and mechanical strength. We found Goniopora and Porites had homogenous structure and Acropora had oriented pores and irregular pore size. Acropora had the largest permeability, however, the transverse section was closed and the useful size was limited because of its habitat type. Porites had the smallest pore size and had the lowest permeability. Our data indicated that Goniopora sp. can be considered as the most promising source of scaffolds for bone-tissue engineering because of its high porosity (73%) and that its permeability and mechanics were similar to those in human cancellous bone. In conclusion, we analyzed the impact of the macroporous structure of coral on the permeability and mechanical properties that provide indicators for designing the optimal scaffold for bone-tissue engineering.

AB - Coral has been used for bone grafts since 1970. Because coral has the advantages of good osteoconduction, biocompatibility, and biodegradation, it is also suitable for scaffolds used in bone-tissue engineering. However, the skeletons of different species of corals often vary significantly, and very few studies focus on the assessment of the permeability and mechanical properties of coral structure. In order to better understand the use of coral in bone tissue-engineering, we selected three typical models (Acropora sp., Goniopora sp., and Porites sp.) to analyze for pore size, porosity, permeability, and mechanical strength. We found Goniopora and Porites had homogenous structure and Acropora had oriented pores and irregular pore size. Acropora had the largest permeability, however, the transverse section was closed and the useful size was limited because of its habitat type. Porites had the smallest pore size and had the lowest permeability. Our data indicated that Goniopora sp. can be considered as the most promising source of scaffolds for bone-tissue engineering because of its high porosity (73%) and that its permeability and mechanics were similar to those in human cancellous bone. In conclusion, we analyzed the impact of the macroporous structure of coral on the permeability and mechanical properties that provide indicators for designing the optimal scaffold for bone-tissue engineering.

UR - http://www.scopus.com/inward/record.url?scp=67349282020&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67349282020&partnerID=8YFLogxK

U2 - 10.1007/s10856-009-3695-3

DO - 10.1007/s10856-009-3695-3

M3 - Article

C2 - 19267261

AN - SCOPUS:67349282020

VL - 20

SP - 1273

EP - 1280

JO - Journal of Materials Science: Materials in Electronics

JF - Journal of Materials Science: Materials in Electronics

SN - 0957-4522

IS - 6

ER -