A composite film prepared from titanium carbide Ti3C2Tx (MXene) and gold nanoparticles for voltammetric determination of uric acid and folic acid

Satheeshkumar Elumalai, Veerappan Mani, Nithiya Jeromiyas, Vinoth Kumar Ponnusamy, Masahiro Yoshimura

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Abstract

In this study, a solution-processing based galvanic deposition approach is described for in-situ deposition of gold nanoparticles (AuNP) on delaminated titanium Ti3C2Tx nanosheets under ultrasonication. The nanocomposite (AuNP@Ti3C2Tx) was placed on a glassy carbon electrode (GCE) and then applied to electrochemically with label-free, and simultaneously sense uric acid (UA), and folic acid (FA) at physiological pH. The modified GCE has attractive figures of merit: (i) The working potentials for UA and AA are well separated (+0.35 V and 0.70 V vs. Ag|AgCl); (ii) wide linear responses (from 0.03–1520 μM for UA and from 0.02–3580 μM for FA; (iii) good electrochemical sensitivities for both UA and FA (0.53 and 0.494 μAμM−1.cm−2, respectively), and (iv) detection limits of 11.5 nM (UA) and 6.20 nM (FA). The electrode exhibited good repeatability (RSD = 4.4%), acceptable reproducibility (RSD = 4.1%), and excellent stability (91.8% over one-month storage). The method was applied to analyze spiked serum samples, and modified GCE is shown appreciable recoveries (97.1–98.8% and 96.8–98.0% for UA, and FA, respectively). [Figure not available: see fulltext.].

Original languageEnglish
Article number33
JournalMicrochimica Acta
Volume187
Issue number1
DOIs
Publication statusPublished - 2020 Jan 1

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All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

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