A DNA hybridization assay using nanogold-streptavidin, electro-microchip and silver enhancement to analyze impedance signals

C. H. Yeh, Y. H. Chang, H. P. Lin, T. C. Chang, Y. C. Lin

Research output: Contribution to journalConference articlepeer-review

2 Citations (Scopus)

Abstract

This paper reports a novel DNA hybridization detection method using gold-streptavidin conjugates as a reporter, the silver enhancement reaction to magnify the detection signal, a commercial LCR meter to detect the hybridization signal. The relationships between sample concentration and detection signal are discussed and the detection limit for the DNA sample is 0.825 ng/mL. Moreover, the probe specific tests are discussed for different species of bacteria, for same species but different strains, and for same genus but different species.

Original languageEnglish
Pages (from-to)333-336
Number of pages4
JournalProcedia Chemistry
Volume1
Issue number1
DOIs
Publication statusPublished - 2009 Sept
EventEurosensors 23rd Conference - Lausanne, Switzerland
Duration: 2009 Sept 62009 Sept 9

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering

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