A magnetic-bead based microfluidic system for automatic C-reactive protein detection

Wen Bin Lee; Hsin I. Lin; Shu-Chu Shiesh; Gwo Bin Lee

doi:10.1115/MNHMT2009-18446

A magnetic-bead based microfluidic system for automatic C-reactive protein detection

Wen Bin Lee, Hsin I. Lin, Shu-Chu Shiesh, Gwo Bin Lee

Department of Medical Laboratory Science and Biotechnology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

C-reactive protein (CRP) has been used as a common indicator during inflammation process. It has been also reported that CRP concentration in serum can be used for risk assessment of cardiovascular diseases. In this study, a new microfluidic system for automatic measurement of CRP is developed. When compared to our previous work, the new chip can perform the entire measurement process by integrating a new micro-injector with other functional microfluidic devices. Experimental data show that the developed system can automate the entire process within 35 minutes with a high sensitivity. The development of the new system may provide a promising platform for automatic measurement of the CRP for point-of-care applications.

Original language	English
Title of host publication	Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009
Pages	257-260
Number of pages	4
DOIs	https://doi.org/10.1115/MNHMT2009-18446
Publication status	Published - 2010 Jul 12
Event	ASME 2009 Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009 - Shanghai, China Duration: 2009 Dec 18 → 2009 Dec 21

Publication series

Name	Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009
Volume	1

Other

Other	ASME 2009 Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009
Country/Territory	China
City	Shanghai
Period	09-12-18 → 09-12-21

All Science Journal Classification (ASJC) codes

Fluid Flow and Transfer Processes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1115/MNHMT2009-18446

Cite this

Lee, W. B., Lin, H. I., Shiesh, S.-C., & Lee, G. B. (2010). A magnetic-bead based microfluidic system for automatic C-reactive protein detection. In Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009 (pp. 257-260). (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009; Vol. 1). https://doi.org/10.1115/MNHMT2009-18446

Lee, Wen Bin ; Lin, Hsin I. ; Shiesh, Shu-Chu et al. / A magnetic-bead based microfluidic system for automatic C-reactive protein detection. Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. 2010. pp. 257-260 (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009).

@inproceedings{ec86886c76484977bec94b07736471d0,

title = "A magnetic-bead based microfluidic system for automatic C-reactive protein detection",

abstract = "C-reactive protein (CRP) has been used as a common indicator during inflammation process. It has been also reported that CRP concentration in serum can be used for risk assessment of cardiovascular diseases. In this study, a new microfluidic system for automatic measurement of CRP is developed. When compared to our previous work, the new chip can perform the entire measurement process by integrating a new micro-injector with other functional microfluidic devices. Experimental data show that the developed system can automate the entire process within 35 minutes with a high sensitivity. The development of the new system may provide a promising platform for automatic measurement of the CRP for point-of-care applications.",

author = "Lee, {Wen Bin} and Lin, {Hsin I.} and Shu-Chu Shiesh and Lee, {Gwo Bin}",

year = "2010",

month = jul,

day = "12",

doi = "10.1115/MNHMT2009-18446",

language = "English",

isbn = "9780791843895",

series = "Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009",

pages = "257--260",

booktitle = "Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009",

note = "ASME 2009 Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009 ; Conference date: 18-12-2009 Through 21-12-2009",

}

Lee, WB, Lin, HI, Shiesh, S-C & Lee, GB 2010, A magnetic-bead based microfluidic system for automatic C-reactive protein detection. in Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009, vol. 1, pp. 257-260, ASME 2009 Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009, Shanghai, China, 09-12-18. https://doi.org/10.1115/MNHMT2009-18446

A magnetic-bead based microfluidic system for automatic C-reactive protein detection. / Lee, Wen Bin; Lin, Hsin I.; Shiesh, Shu-Chu et al.
Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. 2010. p. 257-260 (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009; Vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - A magnetic-bead based microfluidic system for automatic C-reactive protein detection

AU - Lee, Wen Bin

AU - Lin, Hsin I.

AU - Shiesh, Shu-Chu

AU - Lee, Gwo Bin

PY - 2010/7/12

Y1 - 2010/7/12

N2 - C-reactive protein (CRP) has been used as a common indicator during inflammation process. It has been also reported that CRP concentration in serum can be used for risk assessment of cardiovascular diseases. In this study, a new microfluidic system for automatic measurement of CRP is developed. When compared to our previous work, the new chip can perform the entire measurement process by integrating a new micro-injector with other functional microfluidic devices. Experimental data show that the developed system can automate the entire process within 35 minutes with a high sensitivity. The development of the new system may provide a promising platform for automatic measurement of the CRP for point-of-care applications.

AB - C-reactive protein (CRP) has been used as a common indicator during inflammation process. It has been also reported that CRP concentration in serum can be used for risk assessment of cardiovascular diseases. In this study, a new microfluidic system for automatic measurement of CRP is developed. When compared to our previous work, the new chip can perform the entire measurement process by integrating a new micro-injector with other functional microfluidic devices. Experimental data show that the developed system can automate the entire process within 35 minutes with a high sensitivity. The development of the new system may provide a promising platform for automatic measurement of the CRP for point-of-care applications.

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M3 - Conference contribution

AN - SCOPUS:77954347658

SN - 9780791843895

T3 - Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009

SP - 257

EP - 260

BT - Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009

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Lee WB, Lin HI, Shiesh SC, Lee GB. A magnetic-bead based microfluidic system for automatic C-reactive protein detection. In Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. 2010. p. 257-260. (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009). doi: 10.1115/MNHMT2009-18446

A magnetic-bead based microfluidic system for automatic C-reactive protein detection

Abstract

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All Science Journal Classification (ASJC) codes

UN SDGs

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