A magnetic-bead based microfluidic system for automatic C-reactive protein detection

Wen Bin Lee, Hsin I. Lin, Shu-Chu Shiesh, Gwo Bin Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

C-reactive protein (CRP) has been used as a common indicator during inflammation process. It has been also reported that CRP concentration in serum can be used for risk assessment of cardiovascular diseases. In this study, a new microfluidic system for automatic measurement of CRP is developed. When compared to our previous work, the new chip can perform the entire measurement process by integrating a new micro-injector with other functional microfluidic devices. Experimental data show that the developed system can automate the entire process within 35 minutes with a high sensitivity. The development of the new system may provide a promising platform for automatic measurement of the CRP for point-of-care applications.

Original languageEnglish
Title of host publicationProceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009
Pages257-260
Number of pages4
DOIs
Publication statusPublished - 2010 Jul 12
EventASME 2009 Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009 - Shanghai, China
Duration: 2009 Dec 182009 Dec 21

Publication series

NameProceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009
Volume1

Other

OtherASME 2009 Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009
CountryChina
CityShanghai
Period09-12-1809-12-21

Fingerprint

Microfluidics
C-Reactive Protein
Proteins
Risk assessment

All Science Journal Classification (ASJC) codes

  • Fluid Flow and Transfer Processes

Cite this

Lee, W. B., Lin, H. I., Shiesh, S-C., & Lee, G. B. (2010). A magnetic-bead based microfluidic system for automatic C-reactive protein detection. In Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009 (pp. 257-260). (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009; Vol. 1). https://doi.org/10.1115/MNHMT2009-18446
Lee, Wen Bin ; Lin, Hsin I. ; Shiesh, Shu-Chu ; Lee, Gwo Bin. / A magnetic-bead based microfluidic system for automatic C-reactive protein detection. Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. 2010. pp. 257-260 (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009).
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Lee, WB, Lin, HI, Shiesh, S-C & Lee, GB 2010, A magnetic-bead based microfluidic system for automatic C-reactive protein detection. in Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009, vol. 1, pp. 257-260, ASME 2009 Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009, Shanghai, China, 09-12-18. https://doi.org/10.1115/MNHMT2009-18446

A magnetic-bead based microfluidic system for automatic C-reactive protein detection. / Lee, Wen Bin; Lin, Hsin I.; Shiesh, Shu-Chu; Lee, Gwo Bin.

Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. 2010. p. 257-260 (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009; Vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Lee WB, Lin HI, Shiesh S-C, Lee GB. A magnetic-bead based microfluidic system for automatic C-reactive protein detection. In Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009. 2010. p. 257-260. (Proceedings of the ASME Micro/Nanoscale Heat and Mass Transfer International Conference 2009, MNHMT2009). https://doi.org/10.1115/MNHMT2009-18446