This study developed a micromechanical test method for determination of stiffness of collagen molecules. The novelty includes the adoption of an optical tweezer system for loading a single collagen molecule and the development of a binding technique for gripping the collagen molecule termini for the micromechanical test. This methodology will potentially help us to understand the mechanical properties and functions of collagen ultrastructure.
|Number of pages
|Biochemical and Biophysical Research Communications
|Published - 1997 Mar 6
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Cell Biology