A new dimeric protoberberine alkaloid and other compounds from the tubers of Tinospora dentata

Sio Hong Lam; Shu Duan Jian; Tsong Long Hwang; Po Jen Chen; Hsin Yi Hung; Ping Chung Kuo; Tian Shung Wu

doi:10.1080/14786419.2019.1611809

A new dimeric protoberberine alkaloid and other compounds from the tubers of Tinospora dentata

Sio Hong Lam
, Shu Duan Jian
, Tsong Long Hwang
, Po Jen Chen
, Hsin Yi Hung
, Ping Chung Kuo
, Tian Shung Wu

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A new dimeric quaternary protoberberine alkaloid, bispalmatrubine (1), and thirteen known compounds (2-14) were purified from the tubers of Tinospora dentata. Their structures were determined by spectroscopic and spectrometric analytical methods. Among the isolates, eight compounds were examined for their in vitro anti-inflammatory potential and several tested alkaloids displayed moderate inhibitory effects of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.

Original language	English
Pages (from-to)	17-24
Number of pages	8
Journal	Natural Product Research
Volume	35
Issue number	1
DOIs	https://doi.org/10.1080/14786419.2019.1611809
Publication status	Published - 2021

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Biochemistry
Plant Science
Organic Chemistry

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10.1080/14786419.2019.1611809

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abstract = "A new dimeric quaternary protoberberine alkaloid, bispalmatrubine (1), and thirteen known compounds (2-14) were purified from the tubers of Tinospora dentata. Their structures were determined by spectroscopic and spectrometric analytical methods. Among the isolates, eight compounds were examined for their in vitro anti-inflammatory potential and several tested alkaloids displayed moderate inhibitory effects of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.",

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T1 - A new dimeric protoberberine alkaloid and other compounds from the tubers of Tinospora dentata

AU - Lam, Sio Hong

AU - Jian, Shu Duan

AU - Hwang, Tsong Long

AU - Chen, Po Jen

AU - Hung, Hsin Yi

AU - Kuo, Ping Chung

AU - Wu, Tian Shung

PY - 2021

Y1 - 2021

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IS - 1

ER -

A new dimeric protoberberine alkaloid and other compounds from the tubers of Tinospora dentata

Abstract

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