A new method for cell co-culture using micro-molding in capillaries technology: Study of cell transmigration

Yi Chi Huang, Yi Hsien Huang, Keng Shiang Huang, Li Wha Wu, Yu Cheng Lin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study reports a new cell co-culture method using micro-molding in capillaries (MIMIC) technology that was utilized to observe the transmigration conditions of two types of cells with and without under flow shear stress. In the study, endothelial cells (ECs) and smooth muscle cells (SMCs) were used. In addition, the cell concentration is 20000 cells/µL, the shear stress is 2.17 dyne/cm2, and the isolation distance between two types of cell is 500 µm. Results show that (1) the velocity of SMCs migration was always larger than that of ECs migration before they touched each other, and (2) the velocity of cell migration not under shear stress was bigger than that under shear stress.

Original languageEnglish
Title of host publicationProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
EditorsJean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
PublisherChemical and Biological Microsystems Society
Pages700-702
Number of pages3
ISBN (Electronic)9780979806407
Publication statusPublished - 2007
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
Duration: 2007 Oct 72007 Oct 11

Publication series

NameProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/TerritoryFrance
CityParis
Period07-10-0707-10-11

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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