A positive displacement micropump for microdialysis

James Cunneen; Yu Cheng Lin; Simone Caraffini; James G. Boyd; Peter J. Hesketh; Susan M. Lunte; George S. Wilson

doi:10.1016/S0957-4158(98)00008-7

A positive displacement micropump for microdialysis

James Cunneen, Yu Cheng Lin, Simone Caraffini, James G. Boyd, Peter J. Hesketh, Susan M. Lunte, George S. Wilson

Department of Engineering Science

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Miniature fluid pumps, measuring 15 × 4 × 1 mm, have been microfabricated with silicon, glass, and polyimide. Pumps have been tested with deionized water and 10% glycerol solutions as the working solutions. The pumps have been operated with a pneumatic drive or a pie-zoelectric drive. Flow rates from 0.1 to 110 μl min^-1 have been achieved. The maximum pressure generated by the pumps was 56 cm of water. Pumps have been operated with a dialysis probe and with a microchannel load. The pump lifetime is limited by the degradation in the performance of the polyimide components in the pump. The power consumption was less than 1 mW at a drive frequency of 10 Hz.

Original language	English
Pages (from-to)	561-583
Number of pages	23
Journal	Mechatronics
Volume	8
Issue number	5
DOIs	https://doi.org/10.1016/S0957-4158(98)00008-7
Publication status	Published - 1998 Aug 1

All Science Journal Classification (ASJC) codes

Mechanical Engineering
Electrical and Electronic Engineering
Control and Systems Engineering
Computer Science Applications

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10.1016/S0957-4158(98)00008-7

Cite this

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title = "A positive displacement micropump for microdialysis",

abstract = "Miniature fluid pumps, measuring 15 × 4 × 1 mm, have been microfabricated with silicon, glass, and polyimide. Pumps have been tested with deionized water and 10% glycerol solutions as the working solutions. The pumps have been operated with a pneumatic drive or a pie-zoelectric drive. Flow rates from 0.1 to 110 μl min-1 have been achieved. The maximum pressure generated by the pumps was 56 cm of water. Pumps have been operated with a dialysis probe and with a microchannel load. The pump lifetime is limited by the degradation in the performance of the polyimide components in the pump. The power consumption was less than 1 mW at a drive frequency of 10 Hz.",

author = "James Cunneen and Lin, {Yu Cheng} and Simone Caraffini and Boyd, {James G.} and Hesketh, {Peter J.} and Lunte, {Susan M.} and Wilson, {George S.}",

note = "Funding Information: The work was supported by a grant from the Center for Bioanalytical Research at the University of Kansas. Technical assistance of Tony Cocco and Bob Legis is gratefully acknowledged.",

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AU - Cunneen, James

AU - Lin, Yu Cheng

AU - Caraffini, Simone

AU - Boyd, James G.

AU - Hesketh, Peter J.

AU - Lunte, Susan M.

AU - Wilson, George S.

N1 - Funding Information: The work was supported by a grant from the Center for Bioanalytical Research at the University of Kansas. Technical assistance of Tony Cocco and Bob Legis is gratefully acknowledged.

PY - 1998/8/1

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N2 - Miniature fluid pumps, measuring 15 × 4 × 1 mm, have been microfabricated with silicon, glass, and polyimide. Pumps have been tested with deionized water and 10% glycerol solutions as the working solutions. The pumps have been operated with a pneumatic drive or a pie-zoelectric drive. Flow rates from 0.1 to 110 μl min-1 have been achieved. The maximum pressure generated by the pumps was 56 cm of water. Pumps have been operated with a dialysis probe and with a microchannel load. The pump lifetime is limited by the degradation in the performance of the polyimide components in the pump. The power consumption was less than 1 mW at a drive frequency of 10 Hz.

AB - Miniature fluid pumps, measuring 15 × 4 × 1 mm, have been microfabricated with silicon, glass, and polyimide. Pumps have been tested with deionized water and 10% glycerol solutions as the working solutions. The pumps have been operated with a pneumatic drive or a pie-zoelectric drive. Flow rates from 0.1 to 110 μl min-1 have been achieved. The maximum pressure generated by the pumps was 56 cm of water. Pumps have been operated with a dialysis probe and with a microchannel load. The pump lifetime is limited by the degradation in the performance of the polyimide components in the pump. The power consumption was less than 1 mW at a drive frequency of 10 Hz.

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A positive displacement micropump for microdialysis

Abstract

All Science Journal Classification (ASJC) codes

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