A programmable implantable microstimulator soc with wireless telemetry: Application in closed-loop endocardial stimulation for cardiac pacemaker

Shuenn Yuh Lee, Mario Yucheng Su, Ming Chun Liang, You Yin Chen, Cheng Han Hsieh, Chung Min Yang, Hsin Yi Lai, Jou Wei Lin, Qiang Fang

Research output: Contribution to journalArticlepeer-review

68 Citations (Scopus)

Abstract

A low-power, wireless, and implantable microstimulator system on chip with smart powering management, immediate neural signal acquisition, and wireless rechargeable system is proposed. A system controller with parity checking handles the adjustable stimulus parameters for the stimulated objective. In the current paper, the rat's intra-cardiac electrogram is employed as the stimulated model in the animal study, and it is sensed by a low-voltage and low-power monitoring analog front end. The power management unit, which includes a rectifier, battery charging and detection, and a regulator, is used for the power control of the internal circuits. The stimulation data and required clock are extracted by a phase-locked-loop-based phase shift keying demodulator from an inductive AC signal. The full chip, which consumes 48 $\mu {\rm W}$ only, is fabricated in a TSMC 0.35 $ \mu {\rm m}$ 2P4M standard CMOS process to perform the monitoring and pacing functions with inductively powered communication in the in vivo study.

Original languageEnglish
Article number6101569
Pages (from-to)511-522
Number of pages12
JournalIEEE transactions on biomedical circuits and systems
Volume5
Issue number6
DOIs
Publication statusPublished - 2011 Dec

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Electrical and Electronic Engineering

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