A rapid quantitative measurement using the electro-microchip for ketamine and luteinizing hormone detection

Chia Hsien Yeh; Wei Ting Wang; Zheng Kai Sun; Yu Cheng Lin

doi:10.1109/ICSENS.2011.6127293

A rapid quantitative measurement using the electro-microchip for ketamine and luteinizing hormone detection

Chia Hsien Yeh, Wei Ting Wang, Zheng Kai Sun, Yu Cheng Lin

Department of Engineering Science

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

This study successfully developed the electro-microchip to rapidly detect the ketamine (KET) and luteinizing hormone (LH) concentration by using the competitive and sandwich immunoassay, respectively. Our strategy was that the AuNPs were introduced into the electro-microchip by the specific binding of the antibodies and constructs a "bridge" between two electrodes allowing the electrons to pass. The detectable concentration limits for KET and LH were 50 ng/mL and 20 mIU/mL, respectively. Therefore, the developed electro-microchip has advantages for the smaller sample volume (30 μL), rapid quantitative measurement, and smaller detectable concentration than the commercial detection products (KET: 100 ng/mL, and LH: 80 mIU/mL).

Original language	English
Title of host publication	IEEE Sensors 2011 Conference, SENSORS 2011
Pages	940-942
Number of pages	3
DOIs	https://doi.org/10.1109/ICSENS.2011.6127293
Publication status	Published - 2011
Event	10th IEEE SENSORS Conference 2011, SENSORS 2011 - Limerick, Ireland Duration: 2011 Oct 28 → 2011 Oct 31

Publication series

Name	Proceedings of IEEE Sensors

Other

Other	10th IEEE SENSORS Conference 2011, SENSORS 2011
Country/Territory	Ireland
City	Limerick
Period	11-10-28 → 11-10-31

All Science Journal Classification (ASJC) codes

Electrical and Electronic Engineering

Access to Document

10.1109/ICSENS.2011.6127293

Cite this

@inproceedings{739420afe78f487b99021fd4d17fac3c,

title = "A rapid quantitative measurement using the electro-microchip for ketamine and luteinizing hormone detection",

abstract = "This study successfully developed the electro-microchip to rapidly detect the ketamine (KET) and luteinizing hormone (LH) concentration by using the competitive and sandwich immunoassay, respectively. Our strategy was that the AuNPs were introduced into the electro-microchip by the specific binding of the antibodies and constructs a {"}bridge{"} between two electrodes allowing the electrons to pass. The detectable concentration limits for KET and LH were 50 ng/mL and 20 mIU/mL, respectively. Therefore, the developed electro-microchip has advantages for the smaller sample volume (30 μL), rapid quantitative measurement, and smaller detectable concentration than the commercial detection products (KET: 100 ng/mL, and LH: 80 mIU/mL).",

author = "Yeh, {Chia Hsien} and Wang, {Wei Ting} and Sun, {Zheng Kai} and Lin, {Yu Cheng}",

year = "2011",

doi = "10.1109/ICSENS.2011.6127293",

language = "English",

isbn = "9781424492886",

series = "Proceedings of IEEE Sensors",

pages = "940--942",

booktitle = "IEEE Sensors 2011 Conference, SENSORS 2011",

note = "10th IEEE SENSORS Conference 2011, SENSORS 2011 ; Conference date: 28-10-2011 Through 31-10-2011",

}

Yeh, CH, Wang, WT, Sun, ZK & Lin, YC 2011, A rapid quantitative measurement using the electro-microchip for ketamine and luteinizing hormone detection. in IEEE Sensors 2011 Conference, SENSORS 2011., 6127293, Proceedings of IEEE Sensors, pp. 940-942, 10th IEEE SENSORS Conference 2011, SENSORS 2011, Limerick, Ireland, 11-10-28. https://doi.org/10.1109/ICSENS.2011.6127293

TY - GEN

T1 - A rapid quantitative measurement using the electro-microchip for ketamine and luteinizing hormone detection

AU - Yeh, Chia Hsien

AU - Wang, Wei Ting

AU - Sun, Zheng Kai

AU - Lin, Yu Cheng

PY - 2011

Y1 - 2011

N2 - This study successfully developed the electro-microchip to rapidly detect the ketamine (KET) and luteinizing hormone (LH) concentration by using the competitive and sandwich immunoassay, respectively. Our strategy was that the AuNPs were introduced into the electro-microchip by the specific binding of the antibodies and constructs a "bridge" between two electrodes allowing the electrons to pass. The detectable concentration limits for KET and LH were 50 ng/mL and 20 mIU/mL, respectively. Therefore, the developed electro-microchip has advantages for the smaller sample volume (30 μL), rapid quantitative measurement, and smaller detectable concentration than the commercial detection products (KET: 100 ng/mL, and LH: 80 mIU/mL).

AB - This study successfully developed the electro-microchip to rapidly detect the ketamine (KET) and luteinizing hormone (LH) concentration by using the competitive and sandwich immunoassay, respectively. Our strategy was that the AuNPs were introduced into the electro-microchip by the specific binding of the antibodies and constructs a "bridge" between two electrodes allowing the electrons to pass. The detectable concentration limits for KET and LH were 50 ng/mL and 20 mIU/mL, respectively. Therefore, the developed electro-microchip has advantages for the smaller sample volume (30 μL), rapid quantitative measurement, and smaller detectable concentration than the commercial detection products (KET: 100 ng/mL, and LH: 80 mIU/mL).

UR - http://www.scopus.com/inward/record.url?scp=84863051674&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863051674&partnerID=8YFLogxK

U2 - 10.1109/ICSENS.2011.6127293

DO - 10.1109/ICSENS.2011.6127293

M3 - Conference contribution

AN - SCOPUS:84863051674

SN - 9781424492886

T3 - Proceedings of IEEE Sensors

SP - 940

EP - 942

BT - IEEE Sensors 2011 Conference, SENSORS 2011

T2 - 10th IEEE SENSORS Conference 2011, SENSORS 2011

Y2 - 28 October 2011 through 31 October 2011

ER -

A rapid quantitative measurement using the electro-microchip for ketamine and luteinizing hormone detection

Abstract

Publication series

Other

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this