Acetophenones from acronychia pedunculata and their cancer chemopreventive activity

Chihiro Ito, Mari Hosono, Harukuni Tokuda, Tian Shung Wu, Masataka Itoigawa

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


From the roots of Acronychia pedunculata (L.) Miq. (Rutaceae) collected in Taiwan, six known and three new acetophenones have been isolated. The new compounds were named acrophenones D (1), E (2), and F (3). Of the acetophenones isolated in this study, prenylacronylin (4) and acronyculatin D (10) exhibited significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate-induced Epstein-Barr virus early antigen activation in Raji cells.

Original languageEnglish
Pages (from-to)1299-1302
Number of pages4
JournalNatural Product Communications
Issue number9
Publication statusPublished - 2016 Sep

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine


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