Achieving glycemic control in elderly patients with type 2 diabetes: A critical comparison of current options

Ye Fong Du, Horng Yih Ou, Elizabeth A. Beverly, Ching Ju Chiu

Research output: Contribution to journalReview article

36 Citations (Scopus)

Abstract

The prevalence of type 2 diabetes mellitus (T2DM) is increasing in the elderly. Because of the unique characteristics of elderly people with T2DM, therapeutic strategy and focus should be tailored to suit this population. This article reviews the guidelines and studies related to older people with T2DM worldwide. A few important themes are generalized: 1) the functional and cognitive status is critical for older people with T2DM considering their life expectancy compared to younger counterparts; 2) both severe hypoglycemia and persistent hyperglycemia are deleterious to older adults with T2DM, and both conditions should be avoided when determining therapeutic goals; 3) recently developed guidelines emphasize the avoidance of hypoglycemic episodes in older people, even in the absence of symptoms. In addition, we raise the concern of glycemic variability, and discuss the rationale for the selection of current options in managing this patient population.

Original languageEnglish
Pages (from-to)1963-1980
Number of pages18
JournalClinical Interventions in Aging
Volume9
DOIs
Publication statusPublished - 2014 Nov 18

Fingerprint

Type 2 Diabetes Mellitus
Guidelines
Life Expectancy
Hypoglycemia
Hypoglycemic Agents
Hyperglycemia
Population
Therapeutics

All Science Journal Classification (ASJC) codes

  • Geriatrics and Gerontology

Cite this

@article{6cadead77c684da89a2fb655742feb27,
title = "Achieving glycemic control in elderly patients with type 2 diabetes: A critical comparison of current options",
abstract = "The prevalence of type 2 diabetes mellitus (T2DM) is increasing in the elderly. Because of the unique characteristics of elderly people with T2DM, therapeutic strategy and focus should be tailored to suit this population. This article reviews the guidelines and studies related to older people with T2DM worldwide. A few important themes are generalized: 1) the functional and cognitive status is critical for older people with T2DM considering their life expectancy compared to younger counterparts; 2) both severe hypoglycemia and persistent hyperglycemia are deleterious to older adults with T2DM, and both conditions should be avoided when determining therapeutic goals; 3) recently developed guidelines emphasize the avoidance of hypoglycemic episodes in older people, even in the absence of symptoms. In addition, we raise the concern of glycemic variability, and discuss the rationale for the selection of current options in managing this patient population.",
author = "Du, {Ye Fong} and Ou, {Horng Yih} and Beverly, {Elizabeth A.} and Chiu, {Ching Ju}",
year = "2014",
month = "11",
day = "18",
doi = "10.2147/CIA.S53482",
language = "English",
volume = "9",
pages = "1963--1980",
journal = "Clinical Interventions in Aging",
issn = "1176-9092",
publisher = "Dove Medical Press Ltd.",

}

Achieving glycemic control in elderly patients with type 2 diabetes : A critical comparison of current options. / Du, Ye Fong; Ou, Horng Yih; Beverly, Elizabeth A.; Chiu, Ching Ju.

In: Clinical Interventions in Aging, Vol. 9, 18.11.2014, p. 1963-1980.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Achieving glycemic control in elderly patients with type 2 diabetes

T2 - A critical comparison of current options

AU - Du, Ye Fong

AU - Ou, Horng Yih

AU - Beverly, Elizabeth A.

AU - Chiu, Ching Ju

PY - 2014/11/18

Y1 - 2014/11/18

N2 - The prevalence of type 2 diabetes mellitus (T2DM) is increasing in the elderly. Because of the unique characteristics of elderly people with T2DM, therapeutic strategy and focus should be tailored to suit this population. This article reviews the guidelines and studies related to older people with T2DM worldwide. A few important themes are generalized: 1) the functional and cognitive status is critical for older people with T2DM considering their life expectancy compared to younger counterparts; 2) both severe hypoglycemia and persistent hyperglycemia are deleterious to older adults with T2DM, and both conditions should be avoided when determining therapeutic goals; 3) recently developed guidelines emphasize the avoidance of hypoglycemic episodes in older people, even in the absence of symptoms. In addition, we raise the concern of glycemic variability, and discuss the rationale for the selection of current options in managing this patient population.

AB - The prevalence of type 2 diabetes mellitus (T2DM) is increasing in the elderly. Because of the unique characteristics of elderly people with T2DM, therapeutic strategy and focus should be tailored to suit this population. This article reviews the guidelines and studies related to older people with T2DM worldwide. A few important themes are generalized: 1) the functional and cognitive status is critical for older people with T2DM considering their life expectancy compared to younger counterparts; 2) both severe hypoglycemia and persistent hyperglycemia are deleterious to older adults with T2DM, and both conditions should be avoided when determining therapeutic goals; 3) recently developed guidelines emphasize the avoidance of hypoglycemic episodes in older people, even in the absence of symptoms. In addition, we raise the concern of glycemic variability, and discuss the rationale for the selection of current options in managing this patient population.

UR - http://www.scopus.com/inward/record.url?scp=84923312755&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84923312755&partnerID=8YFLogxK

U2 - 10.2147/CIA.S53482

DO - 10.2147/CIA.S53482

M3 - Review article

C2 - 25429208

AN - SCOPUS:84923312755

VL - 9

SP - 1963

EP - 1980

JO - Clinical Interventions in Aging

JF - Clinical Interventions in Aging

SN - 1176-9092

ER -