Abstract
Human immunodeficiency virus type 1 (HIV-1) infection has a broad spectrum of clinical manifestations, ranging from asymptomatic seroconversion to a severe symptomatic illness resembling infectious mononucleosis or other medical conditions including hepatitis, meningoencephalitis, or pneumonitis. Without clinical alertness, the illness is usually misdiagnosed or even not considered. Here we report 3 cases of acute HIV-1 infection with either a negative HIV-1 antibody assay or an indeterminate Western blot result, but high plasma levels of HIV-1 RNA. The initial presentations included fever, skin rash, sore throat, neck lymphadenopathy, cough and headache. One patient presented with infectious mononucleosis-like illness, 1 with aseptic meningitis, and 1 with acute tonsillitis. Physicians should be alert to the possibility of acute HIV-1 infection, especially in cases with unexplained fever, lymphadenopathy or rash.
Original language | English |
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Pages (from-to) | 65-68 |
Number of pages | 4 |
Journal | Journal of Microbiology, Immunology and Infection |
Volume | 38 |
Issue number | 1 |
Publication status | Published - 2005 Feb |
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- General Immunology and Microbiology
- Microbiology (medical)
- Infectious Diseases