Acute human immunodeficiency virus infection

Shao Tsung Huang, Hsin Chun Lee, Kuan-Hung Liu, Nan-Yao Lee, Wen-Chien Ko

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Human immunodeficiency virus type 1 (HIV-1) infection has a broad spectrum of clinical manifestations, ranging from asymptomatic seroconversion to a severe symptomatic illness resembling infectious mononucleosis or other medical conditions including hepatitis, meningoencephalitis, or pneumonitis. Without clinical alertness, the illness is usually misdiagnosed or even not considered. Here we report 3 cases of acute HIV-1 infection with either a negative HIV-1 antibody assay or an indeterminate Western blot result, but high plasma levels of HIV-1 RNA. The initial presentations included fever, skin rash, sore throat, neck lymphadenopathy, cough and headache. One patient presented with infectious mononucleosis-like illness, 1 with aseptic meningitis, and 1 with acute tonsillitis. Physicians should be alert to the possibility of acute HIV-1 infection, especially in cases with unexplained fever, lymphadenopathy or rash.

Original languageEnglish
Pages (from-to)65-68
Number of pages4
JournalJournal of Microbiology, Immunology and Infection
Volume38
Issue number1
Publication statusPublished - 2005 Feb 1

Fingerprint

Virus Diseases
HIV-1
HIV
Infectious Mononucleosis
Exanthema
Fever
Primary Headache Disorders
Aseptic Meningitis
Tonsillitis
Meningoencephalitis
Pharyngitis
Diagnostic Errors
Hepatitis
Pneumonia
Neck
Western Blotting
RNA
Physicians
Antibodies
Lymphadenopathy

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Immunology and Allergy
  • Immunology and Microbiology(all)

Cite this

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Acute human immunodeficiency virus infection. / Huang, Shao Tsung; Lee, Hsin Chun; Liu, Kuan-Hung; Lee, Nan-Yao; Ko, Wen-Chien.

In: Journal of Microbiology, Immunology and Infection, Vol. 38, No. 1, 01.02.2005, p. 65-68.

Research output: Contribution to journalArticle

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