Aetiology of sexually transmitted disease (STD) and comparison of STD syndromes and aetiological diagnosis in Taipei, Taiwan

M. C. Yu, L. H. Li, T. H. Lu, L. H. Tang, C. H. Tsai, K. T. Chen

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Between July 2002 and July 2004, all male patients (n = 307) presenting to a sexually transmitted disease (STD) clinic who reported unprotected sex were enrolled in the study. Of these, 63 (20.5%), 19 (6.2%) and one (0.3%) were infected with one, two and three pathogens, respectively. The prevalences of chlamydial infection, gonorrhoea, syphilis, human immunodeficiency virus infection and trichomoniasis were 14.3%, 10.1%, 6.8%, 2.2% and 0%, respectively. The sensitivities of urethral discharge syndrome for detection of chlamydial, gonococcal, and combined forms of infection were 31.8%, 58.5% and 70.0%, respectively, with specificities of 93.5%, 97.1% and 93.9%, respectively. Positive predictive values (PPVs) were 56.0%, 68.0% and 28.0% for chlamydial and gonococcal infections and combinations of the two forms, respectively. In contrast, the sensitivity of genital ulceration syndrome for syphilis detection was only 38.0%, although the specificity was 82.5%, and the PPV was 32.0%. To reduce the number of false-positive results for STD patients who practise unprotected sex, incorporation of risk assessment and rapid diagnostic tests are recommended.

Original languageEnglish
Pages (from-to)914-918
Number of pages5
JournalClinical Microbiology and Infection
Volume11
Issue number11
DOIs
Publication statusPublished - 2005 Nov

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

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