Ages at different reproductive events, numbers of menstrual cycles in between and breast cancer risk

Wei Chu Chie, Chun Mei Fu, Wen Chung Lee, Chung Yi Li, Chiun Sheng Huang, King Jen Chang, Ruey Shiung Lin

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

One hundred and seventy-five pathologically confirmed new cases of female breast cancer in National Taiwan University Hospital were selected as the case group. Four hundred and fifty-seven inpatient controls were individually matched for each case by age and date of admission. Information of reproductive factors and potential confounders were collected from questionnaire interview and medical records. Menstrual cycles before and after first fullterm pregnancy were estimated from the questionnaire. Conditional logistic regression was used to estimate the effects of reproductive risk factors and numbers of menstrual cycles before and after first full-term pregnancy. After adjusting for educational level, body mass index, family history of breast cancer and oral contraceptive use, age at menarche and menopause only showed borderline significance. Age at first full-term birth predicted breast cancer risk better. Parity was the most important protective factor. Number of menstrual cycles before first full- term pregnancy was also positively associated with breast cancer risk with linear trends.

Original languageEnglish
Pages (from-to)1039-1043
Number of pages5
JournalOncology Reports
Volume4
Issue number5
DOIs
Publication statusPublished - 1997
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Ages at different reproductive events, numbers of menstrual cycles in between and breast cancer risk'. Together they form a unique fingerprint.

Cite this