Aggressive resection of the airway invaded by thyroid carcinoma

Y. F. Tsai, Y. L. Tseng, M. H. Wu, C. J. Hung, W. W. Lai, M. Y. Lin

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)


Background: The aim of this study was to investigate the hypothesis that outcome following concomitant airway resection is superior to that after shaving of the tumour in patients with airway invasion of thyroid carcinoma. Methods: The records of 34 patients with thyroid cancer with airway invasion were reviewed retrospectively. In addition to total thyroidectomy, airway resection was performed in 18 patients (group 1), whereas the tumour was shaved away from the airway in the other 16 patients (group 2). 131I was used as postoperative adjuvant therapy in all patients. Metastasis and recurrence of the primary lesion were determined by 131I whole-body scans, serum thyroglobulin levels, and computed tomography or ultrasonography of the neck. Results: In group 1, two anastomotic dehiscences resulted in one death. Patients in group 2 had a higher rate of local recurrence (relative risk 8.0, P = 0.013) and earlier recurrence (mean(s.e.m.) 2.6(0.8) versus 7.0(1.1) years; P = 0.026) than those in group 1. Median survival was 5.8 and 4.3 years in the 18 patients of group 1 and 16 patients of group 2 (P = 0.259), and the respective 5-year survival rates were 88 and 84 per cent (P = 0.783). Conclusion: Aggressive airway resection can minimize local recurrence of thyroid carcinoma with airway invasion.

Original languageEnglish
Pages (from-to)1382-1387
Number of pages6
JournalBritish Journal of Surgery
Issue number11
Publication statusPublished - 2005 Nov

All Science Journal Classification (ASJC) codes

  • Surgery


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