Alkaloidal and other constituents from the root bark of Clausena excavata

Tian Shung Wu; Shiow Chyn Huang; Pei Lin Wu; Chang Sheng Kuoh

doi:10.1016/S0031-9422(99)00220-4

Alkaloidal and other constituents from the root bark of Clausena excavata

Tian Shung Wu, Shiow Chyn Huang, Pei Lin Wu, Chang Sheng Kuoh

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

90 Citations (Scopus)

Abstract

Ten new carbazole alkaloids, clausine-M, -N, -O, -P, -Q, -R, -S, -U, -V and clausenatine-A, together with 39 known compounds were isolated and identified from the acetone extract of the root bark of Clausena excavata. Their structures have been elucidated by spectroscopic analyses. This is the first report of a decarboxylated carbazole alkaloid from a natural source. The presence of a C(23)-skeleton carbazole alkaloid in a plant of Clausena genus is also reported for the first time.

Original language	English
Pages (from-to)	523-527
Number of pages	5
Journal	Phytochemistry
Volume	52
Issue number	3
DOIs	https://doi.org/10.1016/S0031-9422(99)00220-4
Publication status	Published - 1999 Oct

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Plant Science
Horticulture

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@article{1da8d062a6d2450597964227447753d6,

title = "Alkaloidal and other constituents from the root bark of Clausena excavata",

abstract = "Ten new carbazole alkaloids, clausine-M, -N, -O, -P, -Q, -R, -S, -U, -V and clausenatine-A, together with 39 known compounds were isolated and identified from the acetone extract of the root bark of Clausena excavata. Their structures have been elucidated by spectroscopic analyses. This is the first report of a decarboxylated carbazole alkaloid from a natural source. The presence of a C(23)-skeleton carbazole alkaloid in a plant of Clausena genus is also reported for the first time.",

author = "Wu, {Tian Shung} and Huang, {Shiow Chyn} and Wu, {Pei Lin} and Kuoh, {Chang Sheng}",

note = "Funding Information: We thank the National Science Council, ROC (NSC 81-0420-B-006-10) for support of this research. ",

year = "1999",

month = oct,

doi = "10.1016/S0031-9422(99)00220-4",

language = "English",

volume = "52",

pages = "523--527",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Elsevier Limited",

number = "3",

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T1 - Alkaloidal and other constituents from the root bark of Clausena excavata

AU - Wu, Tian Shung

AU - Huang, Shiow Chyn

AU - Wu, Pei Lin

AU - Kuoh, Chang Sheng

N1 - Funding Information: We thank the National Science Council, ROC (NSC 81-0420-B-006-10) for support of this research.

PY - 1999/10

Y1 - 1999/10

N2 - Ten new carbazole alkaloids, clausine-M, -N, -O, -P, -Q, -R, -S, -U, -V and clausenatine-A, together with 39 known compounds were isolated and identified from the acetone extract of the root bark of Clausena excavata. Their structures have been elucidated by spectroscopic analyses. This is the first report of a decarboxylated carbazole alkaloid from a natural source. The presence of a C(23)-skeleton carbazole alkaloid in a plant of Clausena genus is also reported for the first time.

AB - Ten new carbazole alkaloids, clausine-M, -N, -O, -P, -Q, -R, -S, -U, -V and clausenatine-A, together with 39 known compounds were isolated and identified from the acetone extract of the root bark of Clausena excavata. Their structures have been elucidated by spectroscopic analyses. This is the first report of a decarboxylated carbazole alkaloid from a natural source. The presence of a C(23)-skeleton carbazole alkaloid in a plant of Clausena genus is also reported for the first time.

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JO - Phytochemistry

JF - Phytochemistry

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