Alkyl-poly(l -threonine)/Cyclodextrin Supramolecular Hydrogels with Different Molecular Assemblies and Gel Properties

Sheng Shu Hou, Yu Yun Hsu, Jia Hsien Lin, Jeng Shiung Jan

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

We report alkyl-poly(l-threonine)/cyclodextrin (alkyl-PLT/CD) supramolecular hydrogels with different molecular assemblies. Their properties are determined by the interplay between host-guest chemistry and hydrogen-bonding interactions. The gelation process was mainly dictated by the formation of alkyl chain/CD inclusion complex and PLT chain conformation. The dodecyl-PLT20/α-CD hydrogel exhibited laminar packing due to the sheet-to-coil conformational change upon forming inclusion complex. The hexadecyl-PLT20/β-CD hydrogel exhibited ribbon-like assemblies instead, because the peptide adopted mainly sheet conformation. The gel-to-sol transition occurred upon increasing temperature because of the decrease in hydrogen-bonding interactions and partly conformational change.

Original languageEnglish
Pages (from-to)1201-1205
Number of pages5
JournalACS Macro Letters
Volume5
Issue number11
DOIs
Publication statusPublished - 2016 Nov 15

All Science Journal Classification (ASJC) codes

  • Organic Chemistry
  • Polymers and Plastics
  • Inorganic Chemistry
  • Materials Chemistry

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