An 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)-immobilized electrode for the simultaneous detection of dopamine and uric acid in the presence of ascorbic acid

Yi Kai Chih, Ming Chang Yang

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

An 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS)-immobilized carbon nanotube (CNT) electrode was used to simultaneously detect dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA) with differential pulse voltammetry. When ABTS was immobilized onto the CNT electrode in the presence of DA, UA and 100. μM AA, the sensitivity to DA increased from 0.600 (±0.013) to 1.334 (±0.010). μA/μM in the concentration ranges of 0.90-10. μM and 1.87-20. μM, respectively, and the sensitivity to UA increased from 0.030 (±0.005) to 0.078 (±0.006). μA/μM in the concentration ranges of 2.16-240. μM and 3.07-400. μM, respectively. These findings demonstrate that the ABTS-immobilized CNT electrode attained a higher sensitivity to UA and also a wider linear range of concentrations.

Original languageEnglish
Pages (from-to)44-51
Number of pages8
JournalBioelectrochemistry
Volume91
DOIs
Publication statusPublished - 2013 Jun

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Physical and Theoretical Chemistry
  • Electrochemistry

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