TY - JOUR
T1 - An affinity sensor improved by ewod actuator-based microfluidic chip
AU - Liu, Chin Wei
AU - Lin, Chi Chang
AU - Chen, Li Chia
AU - Fan, Shih Kang
AU - Chang, Hsien Chang
N1 - Funding Information:
The present study was supported by the Landmark Project (D97-2720) of National Cheng Kung University, Taiwan.
PY - 2009/12
Y1 - 2009/12
N2 - We propose an improved immunoassay method with EWOD-based microfluidic biochip. Electro-wetting on dielectric (EWOD) is based on contact angle-changed phenomenon of droplet on the channel surface. The reactant-containing droplet can be moved from reservoir to a modified electrode area, which a stir function can be provided by controlling AC electro-osmosis flow (ACEOF). The immunochemistry reaction takes place on our modified area via electro-wetting actuation, and the signal from fluorescent or electrochemical impedance spectroscopy (EIS) was used to confirm the performance of designed element.
AB - We propose an improved immunoassay method with EWOD-based microfluidic biochip. Electro-wetting on dielectric (EWOD) is based on contact angle-changed phenomenon of droplet on the channel surface. The reactant-containing droplet can be moved from reservoir to a modified electrode area, which a stir function can be provided by controlling AC electro-osmosis flow (ACEOF). The immunochemistry reaction takes place on our modified area via electro-wetting actuation, and the signal from fluorescent or electrochemical impedance spectroscopy (EIS) was used to confirm the performance of designed element.
UR - http://www.scopus.com/inward/record.url?scp=74349110622&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=74349110622&partnerID=8YFLogxK
U2 - 10.4015/S1016237209001659
DO - 10.4015/S1016237209001659
M3 - Article
AN - SCOPUS:74349110622
SN - 1016-2372
VL - 21
SP - 461
EP - 465
JO - Biomedical Engineering - Applications, Basis and Communications
JF - Biomedical Engineering - Applications, Basis and Communications
IS - 6
ER -