An affinity sensor improved by ewod actuator-based microfluidic chip

Chin Wei Liu, Chi Chang Lin, Li Chia Chen, Shih Kang Fan, Hsien Chang Chang

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


We propose an improved immunoassay method with EWOD-based microfluidic biochip. Electro-wetting on dielectric (EWOD) is based on contact angle-changed phenomenon of droplet on the channel surface. The reactant-containing droplet can be moved from reservoir to a modified electrode area, which a stir function can be provided by controlling AC electro-osmosis flow (ACEOF). The immunochemistry reaction takes place on our modified area via electro-wetting actuation, and the signal from fluorescent or electrochemical impedance spectroscopy (EIS) was used to confirm the performance of designed element.

Original languageEnglish
Pages (from-to)461-465
Number of pages5
JournalBiomedical Engineering - Applications, Basis and Communications
Issue number6
Publication statusPublished - 2009 Dec

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomedical Engineering


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