An automatic diagnostic system for CT liver image classification

E. Liang Chen, Pau Choo Chung, Ching Liang Chen, Hong Ming Tsai, Chein I. Chang

Research output: Contribution to journalArticlepeer-review

240 Citations (Scopus)


Computed tomography (CT) images have been widely used for liver disease diagnosis. Designing and developing computer-assisted image processing techniques to help doctors improve their diagnosis has received considerable interests over the past years. In this paper, a CT liver image diagnostic classification system is presented which will automatically find, extract the CT liver boundary and further classify liver diseases. The system comprises a detect-before-extract (DBE) system which automatically finds the liver boundary and a neural network liver classifier which uses specially designed feature descriptors to distinguish normal liver, two types of liver tumors, hepatoma and hemageoma. The DBE system applies the concept of the normalized fractional Brownian motion model to find an initial liver boundary and then uses a deformable contour model to precisely delineate the liver boundary. The neural network is included to classify liver tumors into hepatoma and hemageoma. It is implemented by a modified probabilistic neural network (PNN) [MPNN] in conjunction with feature descriptors which are generated by fractal feature information and the gray-level co-occurrence matrix. The proposed system was evaluated by 30 liver cases and shown to be efficient and very effective.

Original languageEnglish
Pages (from-to)783-794
Number of pages12
JournalIEEE Transactions on Biomedical Engineering
Issue number6
Publication statusPublished - 1998 Jun

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering


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