Abstract
An efficient, mild and scalable synthesis of angelicin scaffold based compounds was developed. Particularly, the new synthetic route described here circumvents the need for the previously reported key Fries rearrangement step, which uses impractically harsh conditions. The new methodology is applied to the synthesis of several, previously reported analogs of angelicin which have potent anti-influenza and anti-cancer activities.
Original language | English |
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Pages (from-to) | 1548-1554 |
Number of pages | 7 |
Journal | Journal of the Chinese Chemical Society |
Volume | 59 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2012 Dec |
All Science Journal Classification (ASJC) codes
- Chemistry(all)