An efficient total synthesis of Benzocamphorin H and its anti-inflammatory activity

Yu Ren Liao, Ping Chung Kuo, Shiow Chyn Huang, Jun Weil Liang, Tian Shung Wu

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

A naturally occurring enynyl-benzenoid, Benzocamphorin H (1), from the edible fungus Taiwanofungus camphoratus (Antrodia camphorata) was characterized by the comprehensive spectral analysis. It displayed potent anti-inflammatory bioactivity and would be valuable for further biological studies. The present study is the first total synthesis of Benzocamphorin H and the developed strategy described a more efficient procedure that allowed large-scale production of Benzocamphorin H for the further research of biological activity both in vitro and in vivo.

Original languageEnglish
Pages (from-to)6202-6204
Number of pages3
JournalTetrahedron Letters
Volume53
Issue number46
DOIs
Publication statusPublished - 2012 Nov 14

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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