An eigen-support differential operator to fuse CT and MR images for nasopharyngeal carcinoma diagnosis

C. Y. Chang, Pau-Choo Chung, W. C. Huang, P. H. Lai

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

One advantage of using instrinsic image properties in medical registration is not necessarily to put fixed markers to identify features which could significantly enlarge the scanning time and cause the patients discomfort. But detecting the same significant landmarks from different image modalities is a high-level image processing task that might prove quite difficult. Using differential geometric features resolves the difficulty of detecting anatomic landmarks. However, operators for differential geometric feature extraction usually generate overwhelming redundant features resulting lack of registration accuracy. In this paper, a second-order differential operator embedded with an eigenimage filter called eigen-Lvv operator is proposed to detect the position of Nasopharyngeal Carcinoma (NPC) in MR images, and then fuse the NPC lesion on the CT image for physicians to comprehend the precise location and tumor range for treatment. The embedded eigenimage filter in this eigen-Lvv operator enhances nasal region, where NPC is located, and suppresses surrounding tissues. Thus, the ridge-like features extracted by the eigen-Lvv operator would focus on the surrounding are of NPC (nasal cavity), aptly avoiding the problem of feature redundancy in most second-order differential operators. A two-stage registration, which consists of a course registration based on geometric contours and a fine registration based on ridge-like anatomical features extracted from eigenimage, is used to reduce the registration time while maintain the registration accuracy. The proposed system has been proven to be effective for NPC detection.

Original languageEnglish
Pages (from-to)101-109
Number of pages9
JournalBiomedical Engineering - Applications, Basis and Communications
Volume12
Issue number3
Publication statusPublished - 2000 Jun 25

Fingerprint

Electric fuses
Redundancy
Feature extraction
Tumors
Image processing
Tissue
Scanning
Anatomic Landmarks
Nasal Cavity
Nose
Nasopharyngeal carcinoma
Physicians
Neoplasms

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomedical Engineering

Cite this

@article{b0178cff0f0d4a8fa42faf37399dd87d,
title = "An eigen-support differential operator to fuse CT and MR images for nasopharyngeal carcinoma diagnosis",
abstract = "One advantage of using instrinsic image properties in medical registration is not necessarily to put fixed markers to identify features which could significantly enlarge the scanning time and cause the patients discomfort. But detecting the same significant landmarks from different image modalities is a high-level image processing task that might prove quite difficult. Using differential geometric features resolves the difficulty of detecting anatomic landmarks. However, operators for differential geometric feature extraction usually generate overwhelming redundant features resulting lack of registration accuracy. In this paper, a second-order differential operator embedded with an eigenimage filter called eigen-Lvv operator is proposed to detect the position of Nasopharyngeal Carcinoma (NPC) in MR images, and then fuse the NPC lesion on the CT image for physicians to comprehend the precise location and tumor range for treatment. The embedded eigenimage filter in this eigen-Lvv operator enhances nasal region, where NPC is located, and suppresses surrounding tissues. Thus, the ridge-like features extracted by the eigen-Lvv operator would focus on the surrounding are of NPC (nasal cavity), aptly avoiding the problem of feature redundancy in most second-order differential operators. A two-stage registration, which consists of a course registration based on geometric contours and a fine registration based on ridge-like anatomical features extracted from eigenimage, is used to reduce the registration time while maintain the registration accuracy. The proposed system has been proven to be effective for NPC detection.",
author = "Chang, {C. Y.} and Pau-Choo Chung and Huang, {W. C.} and Lai, {P. H.}",
year = "2000",
month = "6",
day = "25",
language = "English",
volume = "12",
pages = "101--109",
journal = "Biomedical Engineering - Applications, Basis and Communications",
issn = "1016-2372",
publisher = "World Scientific Publishing Co. Pte Ltd",
number = "3",

}

An eigen-support differential operator to fuse CT and MR images for nasopharyngeal carcinoma diagnosis. / Chang, C. Y.; Chung, Pau-Choo; Huang, W. C.; Lai, P. H.

In: Biomedical Engineering - Applications, Basis and Communications, Vol. 12, No. 3, 25.06.2000, p. 101-109.

Research output: Contribution to journalArticle

TY - JOUR

T1 - An eigen-support differential operator to fuse CT and MR images for nasopharyngeal carcinoma diagnosis

AU - Chang, C. Y.

AU - Chung, Pau-Choo

AU - Huang, W. C.

AU - Lai, P. H.

PY - 2000/6/25

Y1 - 2000/6/25

N2 - One advantage of using instrinsic image properties in medical registration is not necessarily to put fixed markers to identify features which could significantly enlarge the scanning time and cause the patients discomfort. But detecting the same significant landmarks from different image modalities is a high-level image processing task that might prove quite difficult. Using differential geometric features resolves the difficulty of detecting anatomic landmarks. However, operators for differential geometric feature extraction usually generate overwhelming redundant features resulting lack of registration accuracy. In this paper, a second-order differential operator embedded with an eigenimage filter called eigen-Lvv operator is proposed to detect the position of Nasopharyngeal Carcinoma (NPC) in MR images, and then fuse the NPC lesion on the CT image for physicians to comprehend the precise location and tumor range for treatment. The embedded eigenimage filter in this eigen-Lvv operator enhances nasal region, where NPC is located, and suppresses surrounding tissues. Thus, the ridge-like features extracted by the eigen-Lvv operator would focus on the surrounding are of NPC (nasal cavity), aptly avoiding the problem of feature redundancy in most second-order differential operators. A two-stage registration, which consists of a course registration based on geometric contours and a fine registration based on ridge-like anatomical features extracted from eigenimage, is used to reduce the registration time while maintain the registration accuracy. The proposed system has been proven to be effective for NPC detection.

AB - One advantage of using instrinsic image properties in medical registration is not necessarily to put fixed markers to identify features which could significantly enlarge the scanning time and cause the patients discomfort. But detecting the same significant landmarks from different image modalities is a high-level image processing task that might prove quite difficult. Using differential geometric features resolves the difficulty of detecting anatomic landmarks. However, operators for differential geometric feature extraction usually generate overwhelming redundant features resulting lack of registration accuracy. In this paper, a second-order differential operator embedded with an eigenimage filter called eigen-Lvv operator is proposed to detect the position of Nasopharyngeal Carcinoma (NPC) in MR images, and then fuse the NPC lesion on the CT image for physicians to comprehend the precise location and tumor range for treatment. The embedded eigenimage filter in this eigen-Lvv operator enhances nasal region, where NPC is located, and suppresses surrounding tissues. Thus, the ridge-like features extracted by the eigen-Lvv operator would focus on the surrounding are of NPC (nasal cavity), aptly avoiding the problem of feature redundancy in most second-order differential operators. A two-stage registration, which consists of a course registration based on geometric contours and a fine registration based on ridge-like anatomical features extracted from eigenimage, is used to reduce the registration time while maintain the registration accuracy. The proposed system has been proven to be effective for NPC detection.

UR - http://www.scopus.com/inward/record.url?scp=0034713488&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034713488&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0034713488

VL - 12

SP - 101

EP - 109

JO - Biomedical Engineering - Applications, Basis and Communications

JF - Biomedical Engineering - Applications, Basis and Communications

SN - 1016-2372

IS - 3

ER -