Abstract
The fluorescence in situ hybridization (FISH) technique has been commonly employed to determine chromosomal abnormalities. However, it still requires lengthy and labor-intensive sample preparation process. In this study, a new microfluidic chip capable of performing the entire FISH protocol automatically was reported. When compared with the traditional method, several advantages including reduced consumption of biosamples and reagents, automation, fast analysis, can be achieved. Experimental data demonstrated that the developed system can successfully provide superior performance for probing the genetic content of cells at the chromosomal abnormality.
| Original language | English |
|---|---|
| Title of host publication | 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 |
| Pages | 918-921 |
| Number of pages | 4 |
| DOIs | |
| Publication status | Published - 2012 |
| Event | 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 - Paris, France Duration: 2012 Jan 29 → 2012 Feb 2 |
Other
| Other | 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 |
|---|---|
| Country | France |
| City | Paris |
| Period | 12-01-29 → 12-02-02 |
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All Science Journal Classification (ASJC) codes
- Electrical and Electronic Engineering
- Mechanical Engineering
- Condensed Matter Physics
- Electronic, Optical and Magnetic Materials
Cite this
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An integrated microfluidic platform for chromosomal analysis. / Tai, Chien Hsuan; Chen, Ya Lan; Ho, Chung-Liang; Lee, Gwo Bin.
2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012. 2012. p. 918-921 6170335.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
TY - GEN
T1 - An integrated microfluidic platform for chromosomal analysis
AU - Tai, Chien Hsuan
AU - Chen, Ya Lan
AU - Ho, Chung-Liang
AU - Lee, Gwo Bin
PY - 2012
Y1 - 2012
N2 - The fluorescence in situ hybridization (FISH) technique has been commonly employed to determine chromosomal abnormalities. However, it still requires lengthy and labor-intensive sample preparation process. In this study, a new microfluidic chip capable of performing the entire FISH protocol automatically was reported. When compared with the traditional method, several advantages including reduced consumption of biosamples and reagents, automation, fast analysis, can be achieved. Experimental data demonstrated that the developed system can successfully provide superior performance for probing the genetic content of cells at the chromosomal abnormality.
AB - The fluorescence in situ hybridization (FISH) technique has been commonly employed to determine chromosomal abnormalities. However, it still requires lengthy and labor-intensive sample preparation process. In this study, a new microfluidic chip capable of performing the entire FISH protocol automatically was reported. When compared with the traditional method, several advantages including reduced consumption of biosamples and reagents, automation, fast analysis, can be achieved. Experimental data demonstrated that the developed system can successfully provide superior performance for probing the genetic content of cells at the chromosomal abnormality.
UR - http://www.scopus.com/inward/record.url?scp=84860445593&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84860445593&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2012.6170335
DO - 10.1109/MEMSYS.2012.6170335
M3 - Conference contribution
AN - SCOPUS:84860445593
SN - 9781467303248
SP - 918
EP - 921
BT - 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
ER -