Abstract
The fluorescence in situ hybridization (FISH) technique has been commonly employed to determine chromosomal abnormalities. However, it still requires lengthy and labor-intensive sample preparation process. In this study, a new microfluidic chip capable of performing the entire FISH protocol automatically was reported. When compared with the traditional method, several advantages including reduced consumption of biosamples and reagents, automation, fast analysis, can be achieved. Experimental data demonstrated that the developed system can successfully provide superior performance for probing the genetic content of cells at the chromosomal abnormality.
Original language | English |
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Title of host publication | 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 |
Pages | 918-921 |
Number of pages | 4 |
DOIs | |
Publication status | Published - 2012 |
Event | 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 - Paris, France Duration: 2012 Jan 29 → 2012 Feb 2 |
Other
Other | 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 |
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Country | France |
City | Paris |
Period | 12-01-29 → 12-02-02 |
All Science Journal Classification (ASJC) codes
- Electrical and Electronic Engineering
- Mechanical Engineering
- Condensed Matter Physics
- Electronic, Optical and Magnetic Materials