@inproceedings{45ae68b5ab034f078c9b2ae62ec5445b,
title = "An integrated microfluidic system for measurement of troponin I in whole blood by using a membrane-based assay on magnetic beads",
abstract = "This study will use a self-powered stream (STP) technique to develop a point-of-care cassette and based on the urgent need of the Acute myocardial infarction (AMI), we choose Troponin I as the detection target. The integration of the whole blood separation microfluidic cassette and magnetic control platform are used to complete the ultra-low concentration of biomarker. To achieve a high detection goal of the high sensitivity and accuracy of Troponin I, the study has developed three innovative modules: 1. To separate plasma from whole blood sample using the self-powered stream device 2. To locate the reagent at reagent well when plasma separation, a unique design that apply liquid-air surface tension to form the air-gate between reagents. 3. A Troponin I diagnostic cartridge with high sensitivity of 100 pg/mL, coefficient of variation (CV) ≤10%, and assay time ≤ 20 min.",
author = "Chien, {Liang Ju} and Lin, {Yu Ying} and Chiou, {Chi Han} and Kuo, {Shiou Yi} and Chen, {Chih Jen} and Hsieh, {Chih Chia} and Ho, {Tzong Shiann} and Weng, {Chen Hsun}",
year = "2018",
month = jan,
day = "1",
language = "English",
series = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018",
publisher = "Chemical and Biological Microsystems Society",
pages = "2303--2304",
booktitle = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018",
note = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 ; Conference date: 11-11-2018 Through 15-11-2018",
}