An integrated microfluidic system for rapid HbA1c measurement

Ching Chu Wu, Ko Wei Chang, Hsin I. Lin, Shu-Chu Shiesh, Gwo Bin Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Diabetes mellitus (DM) is one of the most prevalent diseases and easily lead to serious complications. Glycosylated hemoglobin (HbA1c), an emerging biomarker for reliable monitoring of DM is commonly detected by bench-top immunoassays, which are labor-intensive and time-consuming. As an advance to existing methods, a microfluidic platform capable of performing automated immunoassay for HbA1c detection within 25 minutes is presented in this work. The microfluidic assay was able to detect HbA1c from human whole blood samples and delivered similar performance as its bench-top counterpart. The developed microfluidic chip is therefore promising for rapid detection of HbA1c for monitoring DM.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages684-686
Number of pages3
ISBN (Print)9781632666246
Publication statusPublished - 2013 Jan 1
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: 2013 Oct 272013 Oct 31

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume1

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period13-10-2713-10-31

All Science Journal Classification (ASJC) codes

  • Bioengineering

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