An inverse problem in estimating the laser irradiance and thermal damage in laser-irradiated biological tissue with a dual-phase-lag model

Yu Ching Yang, Haw Long Lee, Win Jin Chang, Wen Lih Chen

Research output: Contribution to journalArticle

4 Citations (Scopus)


The aim of this study is to solve an inverse heat conduction problem to estimate the unknown time-dependent laser irradiance and thermal damage in laser-irradiated biological tissue from the temperature measurements taken within the tissue. The dual-phase-lag model is considered in the formulation of heat conduction equation. The inverse algorithm used in the study is based on the conjugate gradient method and the discrepancy principle. The effect of measurement errors and measurement locations on the estimation accuracy is also investigated. Two different examples of laser irradiance are discussed. Results show that the unknown laser irradiance and thermal damage can be predicted precisely by using the present approach for the test cases considered in this study.

Original languageEnglish
Pages (from-to)446-456
Number of pages11
JournalComputer Methods in Biomechanics and Biomedical Engineering
Issue number4
Publication statusPublished - 2017 Mar 12


All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biomedical Engineering
  • Human-Computer Interaction
  • Computer Science Applications

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