Analysis of a diffusion-model-based approach for efficient quantification of superficial tissue properties

Sheng Hao Tseng, Ming Feng Hou

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Previously, we reported using a diffusing probe in conjunction with a two-layer diffusion model for accurately recovering the optical properties of superficial volumes. However, the two-layer diffusion equation is computationally less efficient than a standard diffusion equation (SDE) by 3 orders of magnitude. In this Letter, we present a new approach extended from the diffusing probe geometry that enables the use of a diffusion model that has efficiency comparable to an SDE. Our Monte Carlo simulation results indicate that this new approach is not only very accurate but also sensitive to the presence of 0.5 mm3 inhomogeneities and could be used for monitoring the early progression of skin melanoma.

Original languageEnglish
Pages (from-to)3739-3741
Number of pages3
JournalOptics Letters
Volume35
Issue number22
DOIs
Publication statusPublished - 2010 Nov 15

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics

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