TY - JOUR
T1 - Analysis of the analogues of aristolochic acid and aristolactam in the plant of Aristolochia genus by HPLC
AU - Jou, Jenq Huei
AU - Li, Chia Ying
AU - Schelonka, Edward P.
AU - Lin, Chun Hua
AU - Wu, Tian Shung
PY - 2004/3
Y1 - 2004/3
N2 - A facile reversed-phase HPLC method for the analysis of aristolochic acid (AA) and aristolactam (AL) analogues was developed and used for the quantitative determination and quality control of the traditional Chinese medicine. Homonymic Chinese crude drugs such as Stephania tetrandra and Aristolochia fanchi Clematis armandii and A. manshuriensis can be easily identified by this method. The quantitative determination of AAs and ALs in 12 species of Aristolochia (A. elegans, A. zollingeriana, A. cucurbitifolia, A. mollis, A. kaempferi, A. shimadii, A. heterophylla, A. debilis, A. foveolata, A. contorta, A. trilobata and A. odoratissima) has been investigated. The chromatograms obtained in this study can serve as fingerprints to identify plant species in the Aristolochia genus, thus avoiding incorrect identification of herbal ingredients in manufacturing traditional Chinese medicine.
AB - A facile reversed-phase HPLC method for the analysis of aristolochic acid (AA) and aristolactam (AL) analogues was developed and used for the quantitative determination and quality control of the traditional Chinese medicine. Homonymic Chinese crude drugs such as Stephania tetrandra and Aristolochia fanchi Clematis armandii and A. manshuriensis can be easily identified by this method. The quantitative determination of AAs and ALs in 12 species of Aristolochia (A. elegans, A. zollingeriana, A. cucurbitifolia, A. mollis, A. kaempferi, A. shimadii, A. heterophylla, A. debilis, A. foveolata, A. contorta, A. trilobata and A. odoratissima) has been investigated. The chromatograms obtained in this study can serve as fingerprints to identify plant species in the Aristolochia genus, thus avoiding incorrect identification of herbal ingredients in manufacturing traditional Chinese medicine.
UR - http://www.scopus.com/inward/record.url?scp=2542570910&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2542570910&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:2542570910
VL - 12
SP - 40
EP - 45
JO - Journal of Food and Drug Analysis
JF - Journal of Food and Drug Analysis
SN - 1021-9498
IS - 1
ER -