Anti-inflammatory diterpenoids from croton tonkinensis

Ping Chung Kuo, Mei Lin Yang, Tsong Long Hwang, Yuan Yu Lai, Yue Chiun Li, Tran Dinh Thang, Tian Shung Wu

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

Phytochemical investigation of the methanolic extract of Croton tonkinensis afforded two known kauranes (1, 2), eight new ent-kauranes (3-10), and 16 known ent-kauranetype diterpenoids (12-27). In addition, 30 known compounds were identified by comparison of their physical and spectroscopic data with reported data. Among the isolated compounds, ent-18-acetoxykaur-16-en-15-one (20) displayed the most significant inhibition of superoxide anion generation and elastase release.

Original languageEnglish
Pages (from-to)230-236
Number of pages7
JournalJournal of Natural Products
Volume76
Issue number2
DOIs
Publication statusPublished - 2013 Feb 22

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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