Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber officinale (ginger)

Bing Hung Chen, Pei Yu Wu, Kuan Ming Chen, Tzu Fun Fu, Hui Min Wang, Chung Yi Chen

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)

Abstract

In the present study on five pure phenolic compounds (1-5) isolated from the rhizomes of Zingiber officinale (ginger) and investigated for their antiallergic potency, rat basophilic leukemia (RBL-2H3) cells were incubated with these compounds and the release of β-hexosaminidase was measured kinetically. The data obtained suggest that ginger rhizomes harbor potent compounds capable of inhibiting allergic reactions and may be useful for the treatment and prevention of allergic diseases.

Original languageEnglish
Pages (from-to)950-953
Number of pages4
JournalJournal of Natural Products
Volume72
Issue number5
DOIs
Publication statusPublished - 2009 May 22

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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