TY - JOUR
T1 - Antibiotic sulfadiazine degradation by persulfate oxidation
T2 - Intermediates dependence of ecotoxicity and the induction of antibiotic resistance genes
AU - Zheng, Heshan
AU - Zhang, Yunfei
AU - Li, Shuo
AU - Feng, Xiaochi
AU - Wu, Qinglian
AU - Kit Leong, Yoong
AU - Chang, Jo Shu
N1 - Funding Information:
The work was supported by the National Natural Science Foundation of China (21906088, 52170039, 51902169), the Heilongjiang Provincial Natural Science Foundation of China (LH2020B023), the National Science Foundation for Post-doctoral Scientists of China (2021T140165), University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province (UNPYSCT-2020067), Heilongjiang Provincial Key Laboratory of Surface Active Agent and Auxiliary (BMHXJKF009). The support from Ministry of Science and Technology (Taiwan) under grant nos. 111-3116-F-006 -004, 111-2621-M-029 -002, 110-2221-E-029 -004 -MY3, is also greatly acknowledged.
Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2023/1
Y1 - 2023/1
N2 - To preserve the water resources, this study has analyzed the ecotoxicity and antibiotic resistance genes (ARGs) induction capacity of sulfadiazine degradation intermediates resulting from persulfate activation oxidation enhanced by ultraviolet, ultrasound and microwave. The five degradation pathways caused by the contribution discrepancy of electron transfer and singlet oxygen (1O2) and variations in the ecotoxicity of different degradation products were analyzed. Microcosm experiment exhibited that the microbial community in actual water changed significantly with SDZ and degradation intermediates, in which the dominant genera were Aeromonas, Cupriavidus, Elizabethkingia and Achromobacter. Except for the selective pressure on bacteria, the degradation intermediates also exert a certain degree or even stronger induction on sulfonamide ARGs (sul4, sul1 and sul2) than SDZ. Furthermore, the potential hosts for sulfonamide ARGs were revealed by network analysis. These results provide a better understanding of antibiotics degradation mechanism and ARGs occurrence, which is useful for controlling the spread of ARGs.
AB - To preserve the water resources, this study has analyzed the ecotoxicity and antibiotic resistance genes (ARGs) induction capacity of sulfadiazine degradation intermediates resulting from persulfate activation oxidation enhanced by ultraviolet, ultrasound and microwave. The five degradation pathways caused by the contribution discrepancy of electron transfer and singlet oxygen (1O2) and variations in the ecotoxicity of different degradation products were analyzed. Microcosm experiment exhibited that the microbial community in actual water changed significantly with SDZ and degradation intermediates, in which the dominant genera were Aeromonas, Cupriavidus, Elizabethkingia and Achromobacter. Except for the selective pressure on bacteria, the degradation intermediates also exert a certain degree or even stronger induction on sulfonamide ARGs (sul4, sul1 and sul2) than SDZ. Furthermore, the potential hosts for sulfonamide ARGs were revealed by network analysis. These results provide a better understanding of antibiotics degradation mechanism and ARGs occurrence, which is useful for controlling the spread of ARGs.
UR - http://www.scopus.com/inward/record.url?scp=85141951699&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85141951699&partnerID=8YFLogxK
U2 - 10.1016/j.biortech.2022.128306
DO - 10.1016/j.biortech.2022.128306
M3 - Article
C2 - 36372382
AN - SCOPUS:85141951699
SN - 0960-8524
VL - 368
JO - Agricultural Wastes
JF - Agricultural Wastes
M1 - 128306
ER -
