Antiplatelet principles from the root of Petasites formosanus

Tian Shung Wu, Mang San Kao, Pei Lin Wu, Fu Wen Lin, Li Shian Shi, Che Ming Teng

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Three bakkenolide-type compounds, bakkenolides-G, -H and deisobutyryl bakkenolide-H were isolated from the roots of Petasites formosanus. The structures were characterized by spectral methods. Bakkenolide-G and -H showed inhibitory activity against platelet activation factor (PAF), whereas deisobutyryl bakkenolide-H and ferulic acid showed inhibitory activity against arachidonic acid (AA) and collagen (Col)-induced aggregation of washed rabbit platelets.

Original languageEnglish
Pages (from-to)901-905
Number of pages5
JournalPhytochemistry
Volume52
Issue number5
DOIs
Publication statusPublished - 1999 Nov 1

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture

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