Application of MEMS technology and engineering in medicine: A new paradigm for facial muscle reanimation

Kimberly Cockerham, Seppo Aro, Wentai Liu, Oxana Pantchenko, Andrea Olmos, Mark Oehlberg, Mohansankar Sivaprakasam, Lauren Crow

Research output: Contribution to journalReview articlepeer-review

11 Citations (Scopus)

Abstract

Translational research may lead to development of micro-electromechanical system-based devices to treat muscle and nerve dysfunctions whose current treatments are inadequate and, at best, palliative. This paper discusses the development of engineered microsystems as a treatment option for palsies of the seventh cranial nerve and the potential application of these devices as a platform technology for treatment of other nervous dysfunctions. The engineering techniques for electrical and chemical stimulation of denervated muscle are discussed along with current caveats from clinical and engineering standpoints. As opposed to current treatments, miniaturized implants offer the possibility of the reduced toxicity and increased specificity of direct drug delivery. As with the increased miniaturization of other technologies, engineering of these increasingly small implantable microsystems holds great promise for the future development of yet smaller, even nanoscale, implantable devices.

Original languageEnglish
Pages (from-to)371-381
Number of pages11
JournalExpert Review of Medical Devices
Volume5
Issue number3
DOIs
Publication statusPublished - 2008

All Science Journal Classification (ASJC) codes

  • Surgery
  • Biomedical Engineering

Fingerprint

Dive into the research topics of 'Application of MEMS technology and engineering in medicine: A new paradigm for facial muscle reanimation'. Together they form a unique fingerprint.

Cite this