Application of technetium-99m-labeled human serum albumin scan to assist surgical treatment of protein-losing enteropathy in Cronkhite-Canada syndrome: Report of a case

Kuo Chih Tseng, Bor-Shyang Sheu, Jenq-Chang Lee, Hong-Ming Tsai, Nan-Tsing Chiu, Yuan Chang Dai

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Cronkhite-Canada syndrome is a rare form of nonhereditary gastrointestinal polyposis associated with ectodermal change and protein-losing enteropathy. Here we report a 63-year-old male presenting with diffuse gastrointestinal polyposis, onychodystrophy, cutaneous pigmentation, alopecia, diarrhea, hypoalbuminemia and lower leg edema. Technetium-99m-labeled human serum albumin scan confirmed the patient to have protein-losing enteropathy, which originated from the transverse and descending colon. Subtotal colectomy was performed. Albumin level and ectodermal change were gradually improved during three years of outpatient clinic follow-up. Based on our finding, Technetium-99m-labeled human serum albumin scintigraphy is helpful to localize the protein-losing origins and surgery is an effective treatment for Cronkhite-Canada syndrome with protein-losing enteropathy.

Original languageEnglish
Pages (from-to)870-873
Number of pages4
JournalDiseases of the Colon and Rectum
Volume48
Issue number4
DOIs
Publication statusPublished - 2005 Apr 1

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Intestinal Polyposis
Protein-Losing Enteropathies
Technetium
Serum Albumin
Skin Pigmentation
Descending Colon
Hypoalbuminemia
Transverse Colon
Colectomy
Alopecia
Ambulatory Care Facilities
Radionuclide Imaging
Albumins
Diarrhea
Edema
Leg
Therapeutics
Proteins

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

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abstract = "Cronkhite-Canada syndrome is a rare form of nonhereditary gastrointestinal polyposis associated with ectodermal change and protein-losing enteropathy. Here we report a 63-year-old male presenting with diffuse gastrointestinal polyposis, onychodystrophy, cutaneous pigmentation, alopecia, diarrhea, hypoalbuminemia and lower leg edema. Technetium-99m-labeled human serum albumin scan confirmed the patient to have protein-losing enteropathy, which originated from the transverse and descending colon. Subtotal colectomy was performed. Albumin level and ectodermal change were gradually improved during three years of outpatient clinic follow-up. Based on our finding, Technetium-99m-labeled human serum albumin scintigraphy is helpful to localize the protein-losing origins and surgery is an effective treatment for Cronkhite-Canada syndrome with protein-losing enteropathy.",
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AU - Tseng, Kuo Chih

AU - Sheu, Bor-Shyang

AU - Lee, Jenq-Chang

AU - Tsai, Hong-Ming

AU - Chiu, Nan-Tsing

AU - Dai, Yuan Chang

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AB - Cronkhite-Canada syndrome is a rare form of nonhereditary gastrointestinal polyposis associated with ectodermal change and protein-losing enteropathy. Here we report a 63-year-old male presenting with diffuse gastrointestinal polyposis, onychodystrophy, cutaneous pigmentation, alopecia, diarrhea, hypoalbuminemia and lower leg edema. Technetium-99m-labeled human serum albumin scan confirmed the patient to have protein-losing enteropathy, which originated from the transverse and descending colon. Subtotal colectomy was performed. Albumin level and ectodermal change were gradually improved during three years of outpatient clinic follow-up. Based on our finding, Technetium-99m-labeled human serum albumin scintigraphy is helpful to localize the protein-losing origins and surgery is an effective treatment for Cronkhite-Canada syndrome with protein-losing enteropathy.

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