Architecture tradeoffs in high density microstimulators for retinal prosthesis

Mohanasankar Sivaprakasam; Wentai Liu; Guoxing Wang; Mingcui Zhou; James D. Weiland; Mark S. Humayun

doi:10.1109/CNE.2005.1419660

Architecture tradeoffs in high density microstimulators for retinal prosthesis

Mohanasankar Sivaprakasam, Wentai Liu, Guoxing Wang, Mingcui Zhou, James D. Weiland, Mark S. Humayun

Department of Biomedical Engineering

Research output: Contribution to conference › Paper › peer-review

6 Citations (Scopus)

Abstract

Electrical stimulation of retinal neurons has been identified as a form of visual prosthesis to restore vision in blind patients affected by Retinitis Pigmentosa (RP) and Age-related Macular Degeneration (AMD) through several studies and experiments. This paper presents the different architectures of microstimulator for high density retinal prosthesis considering both the biomedical and circuit perspectives. The choices for the key aspects of the microstimulator - location of the chip in the eye, electrode configuration, method of stimulation, demultiplexing, stimulation sequence, and communication protocol - are discussed along with the associated tradeoffs for each of them. In addition, a 60-output microstimulator for an implantable retinal prosthesis to be used in future clinical trials, fabricated in 1.2-μm CMOS technology and its measurement results are presented. The chip consists of 60 independently programmable output drivers and a digital controller for managing run-time and configuration data.

Original language	English
Pages	466-469
Number of pages	4
DOIs	https://doi.org/10.1109/CNE.2005.1419660
Publication status	Published - 2005
Event	2nd International IEEE EMBS Conference on Neural Engineering, 2005 - Arlington, VA, United States Duration: 2005 Mar 16 → 2005 Mar 19

Conference

Conference	2nd International IEEE EMBS Conference on Neural Engineering, 2005
Country/Territory	United States
City	Arlington, VA
Period	05-03-16 → 05-03-19

All Science Journal Classification (ASJC) codes

General Engineering

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10.1109/CNE.2005.1419660

Cite this

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abstract = "Electrical stimulation of retinal neurons has been identified as a form of visual prosthesis to restore vision in blind patients affected by Retinitis Pigmentosa (RP) and Age-related Macular Degeneration (AMD) through several studies and experiments. This paper presents the different architectures of microstimulator for high density retinal prosthesis considering both the biomedical and circuit perspectives. The choices for the key aspects of the microstimulator - location of the chip in the eye, electrode configuration, method of stimulation, demultiplexing, stimulation sequence, and communication protocol - are discussed along with the associated tradeoffs for each of them. In addition, a 60-output microstimulator for an implantable retinal prosthesis to be used in future clinical trials, fabricated in 1.2-μm CMOS technology and its measurement results are presented. The chip consists of 60 independently programmable output drivers and a digital controller for managing run-time and configuration data.",

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AU - Liu, Wentai

AU - Wang, Guoxing

AU - Zhou, Mingcui

AU - Weiland, James D.

AU - Humayun, Mark S.

PY - 2005

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AB - Electrical stimulation of retinal neurons has been identified as a form of visual prosthesis to restore vision in blind patients affected by Retinitis Pigmentosa (RP) and Age-related Macular Degeneration (AMD) through several studies and experiments. This paper presents the different architectures of microstimulator for high density retinal prosthesis considering both the biomedical and circuit perspectives. The choices for the key aspects of the microstimulator - location of the chip in the eye, electrode configuration, method of stimulation, demultiplexing, stimulation sequence, and communication protocol - are discussed along with the associated tradeoffs for each of them. In addition, a 60-output microstimulator for an implantable retinal prosthesis to be used in future clinical trials, fabricated in 1.2-μm CMOS technology and its measurement results are presented. The chip consists of 60 independently programmable output drivers and a digital controller for managing run-time and configuration data.

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Architecture tradeoffs in high density microstimulators for retinal prosthesis

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