Are we ready for the global emergence of multidrug-resistant Candida auris in Taiwan?

Po Liang Lu, Wei Lun Liu, Hsiu Jung Lo, Fu Der Wang, Wen-Chien Ko, Po Ren Hsueh, Mao Wang Ho, Chun Eng Liu, Yen Hsu Chen, Yee Chun Chen, Yin Ching Chuang, Shan Chwen Chang

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Candida auris is a recently identified multi-resistant Candida species, first reported in Japan in 2009, and poses a serious global health threat. Lack of awareness of this new Candida species and difficulties with laboratory identification have impacted significantly on outbreak detection and management, and compromised patient outcome. Accordingly, there is an urgent need to raise awareness of healthcare personnel to this emerging pathogen and determine its prevalence, impact, and challenges to the Taiwan healthcare system. Enhanced laboratory testing strategies are needed to differentiate C. auris from other Candida species to provide accurate diagnosis and implement control measures early enough to prevent hospital outbreaks. In this report, we review the key epidemiological, microbiological and clinical characteristics of C. auris and provide the results of a multicenter surveillance study of C. auris in Taiwan. We also conducted a web-based survey to determine awareness of the medical community to C. auris and the capability of Taiwanese hospital laboratories to identify this microorganism. C. auris has not yet been isolated from humans in Taiwan, but the unique features of this microorganism and its ability to reach across international boundaries justify the importance of these initiatives in Taiwan.

Original languageEnglish
Pages (from-to)462-470
Number of pages9
JournalJournal of the Formosan Medical Association
Volume117
Issue number6
DOIs
Publication statusPublished - 2018 Jun 1

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Taiwan
Candida
Disease Outbreaks
Delivery of Health Care
Hospital Laboratories
Multicenter Studies
Japan

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Lu, Po Liang ; Liu, Wei Lun ; Lo, Hsiu Jung ; Wang, Fu Der ; Ko, Wen-Chien ; Hsueh, Po Ren ; Ho, Mao Wang ; Liu, Chun Eng ; Chen, Yen Hsu ; Chen, Yee Chun ; Chuang, Yin Ching ; Chang, Shan Chwen. / Are we ready for the global emergence of multidrug-resistant Candida auris in Taiwan?. In: Journal of the Formosan Medical Association. 2018 ; Vol. 117, No. 6. pp. 462-470.
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abstract = "Candida auris is a recently identified multi-resistant Candida species, first reported in Japan in 2009, and poses a serious global health threat. Lack of awareness of this new Candida species and difficulties with laboratory identification have impacted significantly on outbreak detection and management, and compromised patient outcome. Accordingly, there is an urgent need to raise awareness of healthcare personnel to this emerging pathogen and determine its prevalence, impact, and challenges to the Taiwan healthcare system. Enhanced laboratory testing strategies are needed to differentiate C. auris from other Candida species to provide accurate diagnosis and implement control measures early enough to prevent hospital outbreaks. In this report, we review the key epidemiological, microbiological and clinical characteristics of C. auris and provide the results of a multicenter surveillance study of C. auris in Taiwan. We also conducted a web-based survey to determine awareness of the medical community to C. auris and the capability of Taiwanese hospital laboratories to identify this microorganism. C. auris has not yet been isolated from humans in Taiwan, but the unique features of this microorganism and its ability to reach across international boundaries justify the importance of these initiatives in Taiwan.",
author = "Lu, {Po Liang} and Liu, {Wei Lun} and Lo, {Hsiu Jung} and Wang, {Fu Der} and Wen-Chien Ko and Hsueh, {Po Ren} and Ho, {Mao Wang} and Liu, {Chun Eng} and Chen, {Yen Hsu} and Chen, {Yee Chun} and Chuang, {Yin Ching} and Chang, {Shan Chwen}",
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Lu, PL, Liu, WL, Lo, HJ, Wang, FD, Ko, W-C, Hsueh, PR, Ho, MW, Liu, CE, Chen, YH, Chen, YC, Chuang, YC & Chang, SC 2018, 'Are we ready for the global emergence of multidrug-resistant Candida auris in Taiwan?', Journal of the Formosan Medical Association, vol. 117, no. 6, pp. 462-470. https://doi.org/10.1016/j.jfma.2017.10.005

Are we ready for the global emergence of multidrug-resistant Candida auris in Taiwan? / Lu, Po Liang; Liu, Wei Lun; Lo, Hsiu Jung; Wang, Fu Der; Ko, Wen-Chien; Hsueh, Po Ren; Ho, Mao Wang; Liu, Chun Eng; Chen, Yen Hsu; Chen, Yee Chun; Chuang, Yin Ching; Chang, Shan Chwen.

In: Journal of the Formosan Medical Association, Vol. 117, No. 6, 01.06.2018, p. 462-470.

Research output: Contribution to journalReview article

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T1 - Are we ready for the global emergence of multidrug-resistant Candida auris in Taiwan?

AU - Lu, Po Liang

AU - Liu, Wei Lun

AU - Lo, Hsiu Jung

AU - Wang, Fu Der

AU - Ko, Wen-Chien

AU - Hsueh, Po Ren

AU - Ho, Mao Wang

AU - Liu, Chun Eng

AU - Chen, Yen Hsu

AU - Chen, Yee Chun

AU - Chuang, Yin Ching

AU - Chang, Shan Chwen

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N2 - Candida auris is a recently identified multi-resistant Candida species, first reported in Japan in 2009, and poses a serious global health threat. Lack of awareness of this new Candida species and difficulties with laboratory identification have impacted significantly on outbreak detection and management, and compromised patient outcome. Accordingly, there is an urgent need to raise awareness of healthcare personnel to this emerging pathogen and determine its prevalence, impact, and challenges to the Taiwan healthcare system. Enhanced laboratory testing strategies are needed to differentiate C. auris from other Candida species to provide accurate diagnosis and implement control measures early enough to prevent hospital outbreaks. In this report, we review the key epidemiological, microbiological and clinical characteristics of C. auris and provide the results of a multicenter surveillance study of C. auris in Taiwan. We also conducted a web-based survey to determine awareness of the medical community to C. auris and the capability of Taiwanese hospital laboratories to identify this microorganism. C. auris has not yet been isolated from humans in Taiwan, but the unique features of this microorganism and its ability to reach across international boundaries justify the importance of these initiatives in Taiwan.

AB - Candida auris is a recently identified multi-resistant Candida species, first reported in Japan in 2009, and poses a serious global health threat. Lack of awareness of this new Candida species and difficulties with laboratory identification have impacted significantly on outbreak detection and management, and compromised patient outcome. Accordingly, there is an urgent need to raise awareness of healthcare personnel to this emerging pathogen and determine its prevalence, impact, and challenges to the Taiwan healthcare system. Enhanced laboratory testing strategies are needed to differentiate C. auris from other Candida species to provide accurate diagnosis and implement control measures early enough to prevent hospital outbreaks. In this report, we review the key epidemiological, microbiological and clinical characteristics of C. auris and provide the results of a multicenter surveillance study of C. auris in Taiwan. We also conducted a web-based survey to determine awareness of the medical community to C. auris and the capability of Taiwanese hospital laboratories to identify this microorganism. C. auris has not yet been isolated from humans in Taiwan, but the unique features of this microorganism and its ability to reach across international boundaries justify the importance of these initiatives in Taiwan.

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