Assessment of hemodynamic responses in cerebral ischemic rats using near infrared spectroscopy

Wan Chen Shao, Chun Wei Wu, Chun Man Yuan, Jia Jin Jason Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ischemic stroke is a high prevailing and disease in industrialized countries. A valid animal model is essential to develop an extensive research. Among various models, middle cerebral artery occlusion (MCAO) is one of the common used ischemic stroke animal models. In this study, we evaluate the absorption coefficient, reduced scattering coefficient and hemodynamic responses using near infrared spectroscopy (NIRS). The correlation between NIRS signals and the brain infarction volume was measured from histochemical stain. Through the well correlation about reduced scattering coefficient, NIRS can be an effective tool to evaluate ischemic stroke.

Original languageEnglish
Title of host publication1st Global Conference on Biomedical Engineering and 9th Asian-Pacific Conference on Medical and Biological Engineering
EditorsFong-Chin Su, Ming-Long Yeh, Shyh-Hau Wang
PublisherSpringer Verlag
Pages154-157
Number of pages4
ISBN (Electronic)9783319122618
Publication statusPublished - 2015 Jan 1
Event1st Global Conference on Biomedical Engineering, GCBME 2014 and 9th Asian-Pacific Conference on Medical and Biological Engineering, APCMBE 2014 - Tainan, Taiwan
Duration: 2014 Oct 92014 Oct 12

Publication series

NameIFMBE Proceedings
Volume47
ISSN (Print)1680-0737
ISSN (Electronic)1433-9277

Other

Other1st Global Conference on Biomedical Engineering, GCBME 2014 and 9th Asian-Pacific Conference on Medical and Biological Engineering, APCMBE 2014
CountryTaiwan
CityTainan
Period14-10-0914-10-12

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biomedical Engineering

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  • Cite this

    Shao, W. C., Wu, C. W., Yuan, C. M., & Chen, J. J. J. (2015). Assessment of hemodynamic responses in cerebral ischemic rats using near infrared spectroscopy. In F-C. Su, M-L. Yeh, & S-H. Wang (Eds.), 1st Global Conference on Biomedical Engineering and 9th Asian-Pacific Conference on Medical and Biological Engineering (pp. 154-157). (IFMBE Proceedings; Vol. 47). Springer Verlag.