Association of novelty seeking scores and striatal dopamine D2/D3 receptor availability of healthy volunteers: Single photon emission computed tomography with 123I-iodobenzamide

Hsiang Yu Huang, I. Hui Lee, Kao Ching Chen, Tzung Lieh Yeh, Po See Chen, Yen Kuang Yang, Nan Tsing Chiu, We Jen Yao, Chia Chieh Chen

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

It has been speculated that novelty seeking (NS) behavior is related to the dopaminergic system. Fifty-two subjects completed the Tridimensional Personality Questionnaire and underwent single photon emission computed tomography with 123I-iodobenzamide. A marginally positive correlation was noted between NS and striatal dopamine D2/D3 receptor availability (r = 0.25, p =0.07). A positive association was noted between the NS scores and left striatal D2/D3 receptor availability (r= 0.29, p =0.04). The results suggest that a relationship might exist between NS score and dopaminergic activity.

Original languageEnglish
Pages (from-to)736-739
Number of pages4
JournalJournal of the Formosan Medical Association
Volume109
Issue number10
DOIs
Publication statusPublished - 2010 Oct 1

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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