Autophagy facilitates an IFN-γ response and signal transduction

Yu Ping Chang; Chia Ling Chen; Su O. Chen; Yee Shin Lin; Cheng Chieh Tsai; Wei Ching Huang; Chi Yun Wang; Chia Yuan Hsieh; Pui Ching Choi; Chiou Feng Lin

doi:10.1016/j.micinf.2011.05.008

Autophagy facilitates an IFN-γ response and signal transduction

Yu Ping Chang, Chia Ling Chen, Su O. Chen, Yee Shin Lin, Cheng Chieh Tsai, Wei Ching Huang, Chi Yun Wang, Chia Yuan Hsieh, Pui Ching Choi, Chiou Feng Lin

Department of Microbiology and Immunology

Research output: Contribution to journal › Short survey › peer-review

13 Citations (Scopus)

Abstract

Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.

Original language	English
Pages (from-to)	888-894
Number of pages	7
Journal	Microbes and Infection
Volume	13
Issue number	11
DOIs	https://doi.org/10.1016/j.micinf.2011.05.008
Publication status	Published - 2011 Oct

All Science Journal Classification (ASJC) codes

Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.micinf.2011.05.008

Cite this

@article{6531d01a059b4b12a5c69dfee6d3aad7,

title = "Autophagy facilitates an IFN-γ response and signal transduction",

abstract = "Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.",

author = "Chang, {Yu Ping} and Chen, {Chia Ling} and Chen, {Su O.} and Lin, {Yee Shin} and Tsai, {Cheng Chieh} and Huang, {Wei Ching} and Wang, {Chi Yun} and Hsieh, {Chia Yuan} and Choi, {Pui Ching} and Lin, {Chiou Feng}",

note = "Funding Information: This work was supported by the grant NHRI-EX99-9917NC from the National Health Research Institutes in Taiwan.",

year = "2011",

month = oct,

doi = "10.1016/j.micinf.2011.05.008",

language = "English",

volume = "13",

pages = "888--894",

journal = "Microbes and Infection",

issn = "1286-4579",

publisher = "Elsevier Masson SAS",

number = "11",

}

TY - JOUR

T1 - Autophagy facilitates an IFN-γ response and signal transduction

AU - Chang, Yu Ping

AU - Chen, Chia Ling

AU - Chen, Su O.

AU - Lin, Yee Shin

AU - Tsai, Cheng Chieh

AU - Huang, Wei Ching

AU - Wang, Chi Yun

AU - Hsieh, Chia Yuan

AU - Choi, Pui Ching

AU - Lin, Chiou Feng

N1 - Funding Information: This work was supported by the grant NHRI-EX99-9917NC from the National Health Research Institutes in Taiwan.

PY - 2011/10

Y1 - 2011/10

N2 - Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.

AB - Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.

UR - http://www.scopus.com/inward/record.url?scp=80052363444&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052363444&partnerID=8YFLogxK

U2 - 10.1016/j.micinf.2011.05.008

DO - 10.1016/j.micinf.2011.05.008

M3 - Short survey

C2 - 21664983

AN - SCOPUS:80052363444

SN - 1286-4579

VL - 13

SP - 888

EP - 894

JO - Microbes and Infection

JF - Microbes and Infection

IS - 11

ER -

Autophagy facilitates an IFN-γ response and signal transduction

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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