Autophagy facilitates an IFN-γ response and signal transduction

Yu Ping Chang, Chia Ling Chen, Su O. Chen, Yee Shin Lin, Cheng Chieh Tsai, Wei Ching Huang, Chi Yun Wang, Chia Yuan Hsieh, Pui Ching Choi, Chiou Feng Lin

Research output: Contribution to journalShort surveypeer-review

13 Citations (Scopus)


Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.

Original languageEnglish
Pages (from-to)888-894
Number of pages7
JournalMicrobes and Infection
Issue number11
Publication statusPublished - 2011 Oct

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Infectious Diseases


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