Abstract
The aim of the study was to improve the pre-operative diagnosis of mammary mucinous lesions. All mucinous lesions detected by fine needle aspiration (FNA) and confirmed by histological examination were reviewed by cytological findings, mammographic appearances and sonographic findings. Twenty aspirates had corresponding pathology, including 12 mucinous carcinomas, two mucocele-like lesions (MLL) with atypical ductal hyperplasia, three MLL with ductal hyperplasia and three simple MLL. Simple MLL and mucocele-like with ductal hyperplasia showed scant cellularity, no or rare intact single tumour cells, monolayered arrangement and absence of nuclear atypia. In contrast, most mucinous carcinomas showed higher cellularity, more single tumour cells, three-dimensional dusters, and mild to marked nuclear atypia. However, MLL with atypical ductal hyperplasia showed cytological features overlapping with mucinous carcinoma. MLL had a non-specific mammographic appearance and showed a cystic lesion on sonography. Mucinous carcinoma appeared as a solid mass on sonography and as a distinct nodule on mammography. Based on the combination of FNA cytology and image findings, benign MLL can be correctly distinguished from mucinous carcinoma before surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 104-108 |
| Number of pages | 5 |
| Journal | Cytopathology |
| Volume | 15 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2004 Apr 1 |
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All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Histology
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Benign mucocele-like lesion of the breast : How to differentiate from mucinous carcinoma before surgery. / Cheng, L.; Lee, W. Y.; Chang, T. W.
In: Cytopathology, Vol. 15, No. 2, 01.04.2004, p. 104-108.Research output: Contribution to journal › Article
TY - JOUR
T1 - Benign mucocele-like lesion of the breast
T2 - How to differentiate from mucinous carcinoma before surgery
AU - Cheng, L.
AU - Lee, W. Y.
AU - Chang, T. W.
PY - 2004/4/1
Y1 - 2004/4/1
N2 - The aim of the study was to improve the pre-operative diagnosis of mammary mucinous lesions. All mucinous lesions detected by fine needle aspiration (FNA) and confirmed by histological examination were reviewed by cytological findings, mammographic appearances and sonographic findings. Twenty aspirates had corresponding pathology, including 12 mucinous carcinomas, two mucocele-like lesions (MLL) with atypical ductal hyperplasia, three MLL with ductal hyperplasia and three simple MLL. Simple MLL and mucocele-like with ductal hyperplasia showed scant cellularity, no or rare intact single tumour cells, monolayered arrangement and absence of nuclear atypia. In contrast, most mucinous carcinomas showed higher cellularity, more single tumour cells, three-dimensional dusters, and mild to marked nuclear atypia. However, MLL with atypical ductal hyperplasia showed cytological features overlapping with mucinous carcinoma. MLL had a non-specific mammographic appearance and showed a cystic lesion on sonography. Mucinous carcinoma appeared as a solid mass on sonography and as a distinct nodule on mammography. Based on the combination of FNA cytology and image findings, benign MLL can be correctly distinguished from mucinous carcinoma before surgery.
AB - The aim of the study was to improve the pre-operative diagnosis of mammary mucinous lesions. All mucinous lesions detected by fine needle aspiration (FNA) and confirmed by histological examination were reviewed by cytological findings, mammographic appearances and sonographic findings. Twenty aspirates had corresponding pathology, including 12 mucinous carcinomas, two mucocele-like lesions (MLL) with atypical ductal hyperplasia, three MLL with ductal hyperplasia and three simple MLL. Simple MLL and mucocele-like with ductal hyperplasia showed scant cellularity, no or rare intact single tumour cells, monolayered arrangement and absence of nuclear atypia. In contrast, most mucinous carcinomas showed higher cellularity, more single tumour cells, three-dimensional dusters, and mild to marked nuclear atypia. However, MLL with atypical ductal hyperplasia showed cytological features overlapping with mucinous carcinoma. MLL had a non-specific mammographic appearance and showed a cystic lesion on sonography. Mucinous carcinoma appeared as a solid mass on sonography and as a distinct nodule on mammography. Based on the combination of FNA cytology and image findings, benign MLL can be correctly distinguished from mucinous carcinoma before surgery.
UR - http://www.scopus.com/inward/record.url?scp=1842734282&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1842734282&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2303.2004.00130.x
DO - 10.1111/j.1365-2303.2004.00130.x
M3 - Article
C2 - 15056171
AN - SCOPUS:1842734282
VL - 15
SP - 104
EP - 108
JO - Cytopathology
JF - Cytopathology
SN - 0956-5507
IS - 2
ER -