Bioactive alkaloids from Illigera luzonensis

Keh Shaw Chen, Yang Chang Wu, Che Ming Teng, Feng Nien Ko, Tian-Shung Wu

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Using antiplatelet aggregation as a guide to fractionation, seven aporphines, actinodaphnine (1), N-methylactinodaphnine (2), launobine (3), dicentrine (4), O-methylbulbocapnine (5), hernovine (7), and bulbocapnine (9), and two oxoaporphines, dicentrinone (6) and liriodenine (8), were isolated from the stems of Illigera luzonensis. Among them, compounds 2, 4, 5, 8, and 9 were isolated for the first time from this species. Moreover, compounds 1-5, 7, and 8 showed significant antiplatelet aggregation and compounds 1 and 6 exhibited significant vasorelaxant activities, respectively.

Original languageEnglish
Pages (from-to)645-647
Number of pages3
JournalJournal of Natural Products
Volume60
Issue number6
DOIs
Publication statusPublished - 1997 Jun 1

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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