TY - JOUR
T1 - Birth weight and type 1 diabetes among schoolchildren in Taiwan-A population-based case-controlled study
AU - Wei, Jung Nan
AU - Li, Hung Yuan
AU - Chang, Chia Hsiung
AU - Sung, Fung Chang
AU - Li, Chung Yi
AU - Lin, Chau Ching
AU - Chiang, Chuan Chi
AU - Chuang, Lee Ming
N1 - Funding Information:
This work was supported by the Chinese Foundation of Health and a grant (DOH91-TD1167) from the Department of Health, Executive Yuan, Republic of China.
PY - 2006/12
Y1 - 2006/12
N2 - To explore the relationship between birth weight and type 1 diabetes, data from national birth registry and national surveillance of diabetes in Taiwanese schoolchildren were analyzed. From 1992 to 1997, all schoolchildren aged 6-18 years were screened for diabetes by a mass urine survey program in Taiwan Province. This cohort consisted of 1966 children with diabetes and 1780 of randomly selected subjects with normal fasting glycemia. Questionnaires were designed for telephone interviews with students' parents or physicians to classify subjects' types of diabetes. The birth history of each participant was obtained from the Taiwan's Birth Registry. After merging the data, there were 835 subjects, including 277 of type 1 diabetes and 533 of normal fasting glycemia available for the present analyses. The odds ratio (95% CI) for type 1 diabetes, after adjusting age, sex, socioeconomic status, family history of diabetes, birth order, breast-feeding, BMI, and gestational diabetes mellitus was 2.24 (1.11-4.50) for children with low birth weight (<5th percentile, i.e., ≤2600 g) when compared with the referent group of a birth weight of 3000-3542 g (equivalent to the 25-75th percentile). In conclusion, low birth weight was associated with increased risk of type 1 diabetes in Taiwanese schoolchildren.
AB - To explore the relationship between birth weight and type 1 diabetes, data from national birth registry and national surveillance of diabetes in Taiwanese schoolchildren were analyzed. From 1992 to 1997, all schoolchildren aged 6-18 years were screened for diabetes by a mass urine survey program in Taiwan Province. This cohort consisted of 1966 children with diabetes and 1780 of randomly selected subjects with normal fasting glycemia. Questionnaires were designed for telephone interviews with students' parents or physicians to classify subjects' types of diabetes. The birth history of each participant was obtained from the Taiwan's Birth Registry. After merging the data, there were 835 subjects, including 277 of type 1 diabetes and 533 of normal fasting glycemia available for the present analyses. The odds ratio (95% CI) for type 1 diabetes, after adjusting age, sex, socioeconomic status, family history of diabetes, birth order, breast-feeding, BMI, and gestational diabetes mellitus was 2.24 (1.11-4.50) for children with low birth weight (<5th percentile, i.e., ≤2600 g) when compared with the referent group of a birth weight of 3000-3542 g (equivalent to the 25-75th percentile). In conclusion, low birth weight was associated with increased risk of type 1 diabetes in Taiwanese schoolchildren.
UR - https://www.scopus.com/pages/publications/33749988465
UR - https://www.scopus.com/pages/publications/33749988465#tab=citedBy
U2 - 10.1016/j.diabres.2006.04.018
DO - 10.1016/j.diabres.2006.04.018
M3 - Article
C2 - 16814899
AN - SCOPUS:33749988465
SN - 0168-8227
VL - 74
SP - 309
EP - 315
JO - Diabetes Research and Clinical Practice
JF - Diabetes Research and Clinical Practice
IS - 3
ER -
