C 35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines

Chin Lin Hsieh, Mei Huims Tseng, Yi Yuan Shao, Jang-Yang Chang, Ching Chuan Kuo, Chi Yen Chang, Yueh Hsiung Kuo

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C 35 terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C 35 terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC 50 values ranging from 11 to 14 μM.

Original languageEnglish
Pages (from-to)1611-1613
Number of pages3
JournalJournal of Natural Products
Volume69
Issue number11
DOIs
Publication statusPublished - 2006 Nov 1

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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