Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C 35 terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C 35 terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC 50 values ranging from 11 to 14 μM.
All Science Journal Classification (ASJC) codes
- Analytical Chemistry
- Molecular Medicine
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry