C35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines

Chin Lin Hsieh, Mei Huims Tseng, Yi Yuan Shao, Jang Yang Chang, Ching Chuan Kuo, Chi Yen Chang, Yueh Hsiung Kuo

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C35 terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C35 terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC50 values ranging from 11 to 14 μM.

Original languageEnglish
Pages (from-to)1611-1613
Number of pages3
JournalJournal of Natural Products
Volume69
Issue number11
DOIs
Publication statusPublished - 2006 Nov

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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