C 35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines

Chin Lin Hsieh, Mei Huims Tseng, Yi Yuan Shao, Jang-Yang Chang, Ching Chuan Kuo, Chi Yen Chang, Yueh Hsiung Kuo

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C 35 terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C 35 terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC 50 values ranging from 11 to 14 μM.

Original languageEnglish
Pages (from-to)1611-1613
Number of pages3
JournalJournal of Natural Products
Volume69
Issue number11
DOIs
Publication statusPublished - 2006 Nov 1

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Cupressaceae
Terpenes
Human Activities
Cells
KB Cells
Cell Line
Cytotoxicity
Skeleton
Squamous Cell Carcinoma
Neoplasms

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

Cite this

Hsieh, Chin Lin ; Tseng, Mei Huims ; Shao, Yi Yuan ; Chang, Jang-Yang ; Kuo, Ching Chuan ; Chang, Chi Yen ; Kuo, Yueh Hsiung. / C 35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines In: Journal of Natural Products. 2006 ; Vol. 69, No. 11. pp. 1611-1613.
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C 35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines . / Hsieh, Chin Lin; Tseng, Mei Huims; Shao, Yi Yuan; Chang, Jang-Yang; Kuo, Ching Chuan; Chang, Chi Yen; Kuo, Yueh Hsiung.

In: Journal of Natural Products, Vol. 69, No. 11, 01.11.2006, p. 1611-1613.

Research output: Contribution to journalArticle

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AU - Shao, Yi Yuan

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AU - Kuo, Ching Chuan

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AU - Kuo, Yueh Hsiung

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