C35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines

Chin Lin Hsieh; Mei Huims Tseng; Yi Yuan Shao; Jang Yang Chang; Ching Chuan Kuo; Chi Yen Chang; Yueh Hsiung Kuo

doi:10.1021/np0600550

C₃₅ terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines

Chin Lin Hsieh, Mei Huims Tseng, Yi Yuan Shao, Jang Yang Chang, Ching Chuan Kuo, Chi Yen Chang, Yueh Hsiung Kuo

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C₃₅ terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C₃₅ terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC₅₀ values ranging from 11 to 14 μM.

Original language	English
Pages (from-to)	1611-1613
Number of pages	3
Journal	Journal of Natural Products
Volume	69
Issue number	11
DOIs	https://doi.org/10.1021/np0600550
Publication status	Published - 2006 Nov

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1021/np0600550

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title = "C35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines",

abstract = "Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C35 terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C35 terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC50 values ranging from 11 to 14 μM.",

author = "Hsieh, {Chin Lin} and Tseng, {Mei Huims} and Shao, {Yi Yuan} and Chang, {Jang Yang} and Kuo, {Ching Chuan} and Chang, {Chi Yen} and Kuo, {Yueh Hsiung}",

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AU - Hsieh, Chin Lin

AU - Tseng, Mei Huims

AU - Shao, Yi Yuan

AU - Chang, Jang Yang

AU - Kuo, Ching Chuan

AU - Chang, Chi Yen

AU - Kuo, Yueh Hsiung

PY - 2006/11

Y1 - 2006/11

N2 - Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C35 terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C35 terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC50 values ranging from 11 to 14 μM.

AB - Ferrugicadinol (1) and ferrugieudesmol (2), two new compounds with a unique C35 terpene skeleton, were isolated from the bark of Calocedrus macrolepis var. formosana. Their structures were elucidated principally from spectroscopic evidence. The two new C35 terpenes showed cytotoxicity against human oral epidermoid carcinoma KB cells with IC50 values ranging from 11 to 14 μM.

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IS - 11

ER -

C₃₅ terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines

Abstract

All Science Journal Classification (ASJC) codes

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