Cell culture arrays using micron-sized ferromagnetic ring-shaped thin films

Chen Yu Huang, Mei Feng Lai, Tzong Rong Ger, Zung Hang Wei

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cell patterning has become an important technology for tissue engineering. In this research, domain walls are formed at the two ends of a ferromagnetic ring thin film after applying a strong external magnetic field, which can effectively attract magnetically labeled cells and control the position for biological cell. Magnetophoresis experiment was conducted to quantify the magnetic nanoparticle inside the cells. A ring-shaped magnetic thin films array was fabricated through photolithography. It is observed that magnetically labeled cells can be successfully attracted to the two ends of the ring-shaped magnetic thin film structure and more cells were attracted and further attached to the structures. The cells are co-cultured with the structure and kept proliferating; therefore, such ring thin film can be an important candidate for in-vitro biomedical chips or tissue engineering.

Original languageEnglish
Article number17B309
JournalJournal of Applied Physics
Volume117
Issue number17
DOIs
Publication statusPublished - 2015 May 7

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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