Cell image segmentation method and a nuclear-to-cytoplasmic ratio evaluation method using the same

Gwo-Giun Lee (Inventor)

Research output: Patent


A cell image segmentation method includes receiving a cell image, performing a nuclei initialization step to find an internal marker and an external marker to obtain a potential nuclei and a potential cell boundary, calculating a gradient map of the received cell image, performing a filtering step on the gradient map to generate a filtered gradient map, performing a nuclei detection step to obtain a segmented nuclei, and performing a nuclei validation step to obtain a valid nuclei. The nuclei initialization step includes performing a blob detection step to obtain a nuclei candidate, an outlier removal step to obtain the internal marker,
Translated title of the contribution細胞影像分割方法以及核質比評估方法
Original languageEnglish
Patent numberI496112
Publication statusPublished - 1800

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