Cell response to electrospun PVA and PVA/chitosan nanofibers

J. I. Liang, H. C. Hsu, Y. H. Nien, F. C. Su, H. W. Wu, J. P. Chen, M. L. Yeh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

PVA and chitosan have been used for many tissue engineering applications. However, most of the studies use only single polymer to fabricate nanofibers. Therefore, the purpose of this study is to fabricate PVA and PVA/Chitosan nanofiber scaffold for potential tissue engineering applications. The nanofrous scaffold was produced via electrospinning. NIH 3T3 fibroblast cells were seeded onto scaffolds for different time points. The attached fibroblast cells appeared round shape on the PVA nanofiber scaffold and spindle shape on the PVA/Chitosan nanofiber scaffold. The result shows that the fibroblast exhibit good cell viability and gene expression on the PVA/Chitosan nanofiber scaffold. Therefore, PVA/Chitosan nanofiber scaffold could be the better choice for further applications.

Original languageEnglish
Title of host publicationNEBEC 2009 - Proceedings of the IEEE 35th Annual Northeast Bioengineering Conference
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781424443628
DOIs
Publication statusPublished - 2009
EventIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009 - Boston, MA, United States
Duration: 2009 Apr 32009 Apr 5

Publication series

NameProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
ISSN (Print)1071-121X

Other

OtherIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009
Country/TerritoryUnited States
CityBoston, MA
Period09-04-0309-04-05

All Science Journal Classification (ASJC) codes

  • Bioengineering

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